Multi-omics analysis of canine aging markers and evaluation of stem cell intervention

Abstract Dogs serve as ideal research subjects for aging studies. In this study, 9 aging-related cell populations are identified through single-cell RNA sequencing of dogs of different ages. Additionally, 9 CD8+ T cell senescence-specific markers conserved across species are identified. Furthermore,...

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Bibliographic Details
Main Authors: Balun Li, Yanheng Ding, Miao Han, Zengyu Zhang, Zixi Ling, Wenlong Zhu, Xianjun Zhao, Yihua Zhang, Changrong Lv, Na Li, Mingzhi Liao, Jinlian Hua
Format: Article
Language:English
Published: Nature Portfolio 2025-06-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-025-08333-z
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