Ribosomal protein mutation suppresses gonadal leader cell migration defects in mig-17/ADAMTS mutants in Caenorhabditis elegans

Ribosomal protein mutation suppresses gonadal leader cell migration defects in mig-17/ADAMTS mutants in Caenorhabditis elegans

Abstract The migration of gonadal distal tip cells (DTCs) in Caenorhabditis elegans serves as an excellent model for studying the migration of epithelial tubes during organogenesis. Mutations in the mig-17/ADAMTS gene cause misdirected DTC migration during gonad formation, resulting in deformed gona...

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Bibliographic Details
Main Authors: Hon-Song Kim, Kaito Mitsuzumi, Shohei Kondo, Rie Yamaoka, Shinji Ihara, Hiroshi Otsuka, Chizu Yoshikata, Yukihiko Kubota, Takumi Tomohiro, Toshinobu Fujiwara, Kenji Kimura, Fumio Motegi, Yukimasa Shibata, Mikiko Takahashi, Kiyoji Nishiwaki
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
Subjects:
Ribosome protein mutation
RPL18a/eL20
Growth retardation
ADAMTS
Organogenesis
Online Access:https://doi.org/10.1038/s41598-025-10316-3
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