Effects of Modified Messenger RNA of Adiponectin Delivered by Lipid Nanoparticles on Adipogenesis and Bone Metabolism In Vitro and In Vivo

Effects of Modified Messenger RNA of Adiponectin Delivered by Lipid Nanoparticles on Adipogenesis and Bone Metabolism In Vitro and In Vivo

Adiponectin (APN) is a secreted adipokine that plays a key role in modulating energy and bone metabolism, as well as regulating inflammatory responses. The overexpression of APN has been proposed as a potential therapeutic strategy for treating obesity and related disorders. Lipid nanoparticles (LNP...

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Bibliographic Details
Main Authors: Ying Xie, Qian Ma, Jinghao Wang, Zoe Xiaofang Zhu, Rady E. El-Araby, Maxwell Tu, Zhongyu Li, Xiaoyang Xu, Qisheng Tu, Jake Chen
Format: Article
Language:English
Published: MDPI AG 2025-06-01
Series:Cells
Subjects:
modified mRNA
adiponectin
adipogenesis
osteogenesis
lipid nanoparticles
Online Access:https://www.mdpi.com/2073-4409/14/12/891
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