Simultaneous Determination of Schisandrin and Promethazine with Its Metabolite in Rat Plasma by HPLC-MS/MS and Its Application to a Pharmacokinetic Study

Simultaneous Determination of Schisandrin and Promethazine with Its Metabolite in Rat Plasma by HPLC-MS/MS and Its Application to a Pharmacokinetic Study

This study aimed to develop a selective, simple, and sensitive HPLC-MS/MS method for the simultaneous determination of schisandrin and promethazine (PMZ) with its metabolite in rat plasma, which was further used for a pharmacokinetic herb-drug interaction study. HPLC-MS/MS analyses were performed on...

Full description

Saved in:
Bibliographic Details
Main Authors: Sijia Gao, Xuelin Zhou, Liwei Lang, Honghong Liu, Jianyu Li, Haotian Li, Shizhang Wei, Dan Wang, Zhuo Xu, Huadan Cai, Yanling Zhao, Wenjun Zou
Format: Article
Language:English
Published: Wiley 2019-01-01
Series:International Journal of Analytical Chemistry
Online Access:http://dx.doi.org/10.1155/2019/3497045
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items

Similar Items