Exploring the anti-cancer potential of coumarin derivatives targeting COX-2 inhibitors

Exploring the anti-cancer potential of coumarin derivatives targeting COX-2 inhibitors

Overexpression of cyclooxygenase-2 (COX-2) plays a crucial role in cancer therapy. In this study, we investigated the role of two coumarin derivatives with the chlorobenzylamide group in inhibiting COX-2 activity and growth inhibition of cancer cells. The effect of synthesized 2a and 2b coumarin der...

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Bibliographic Details
Main Authors: Thanh Tin Le, Y Thien Vu, Hieu Minh Doan, Bao Le
Format: Article
Language:English
Published: HO CHI MINH CITY OPEN UNIVERSITY JOURNAL OF SCIENCE 2025-01-01
Series:Ho Chi Minh City Open University Journal of Science - Engineering and Technology
Subjects:
anti-cancer
coumarin
cox-2 inhibitors
synthesis
Online Access:https://journalofscience.ou.edu.vn/index.php/tech-en/article/view/3580
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