Clinico-epidemiological study of oral squamous cell carcinoma: A tertiary care centre study in North India

Introduction: Oral squamous cell carcinoma (OSCC) ranks 12th most common cancer in the world. Objective: The aim of this study was to retrospectively evaluate the OSCC. Methods: A retrospective study of 611 OSCC patients from January 2010 to December 2013 was carried out in Department of Surgical On...

Full description

Saved in:
Bibliographic Details
Main Authors: Mahendra Pratap Singh, Vijay Kumar, Akash Agarwal, Rajendra Kumar, M.L.B. Bhatt, Sanjeev Misra
Format: Article
Language:English
Published: Elsevier 2016-01-01
Series:Journal of Oral Biology and Craniofacial Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2212426815001268
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1850060779801280512
author Mahendra Pratap Singh
Vijay Kumar
Akash Agarwal
Rajendra Kumar
M.L.B. Bhatt
Sanjeev Misra
author_facet Mahendra Pratap Singh
Vijay Kumar
Akash Agarwal
Rajendra Kumar
M.L.B. Bhatt
Sanjeev Misra
author_sort Mahendra Pratap Singh
collection DOAJ
description Introduction: Oral squamous cell carcinoma (OSCC) ranks 12th most common cancer in the world. Objective: The aim of this study was to retrospectively evaluate the OSCC. Methods: A retrospective study of 611 OSCC patients from January 2010 to December 2013 was carried out in Department of Surgical Oncology, King George's Medical University, Lucknow, India. Details of patient's sex, age, tobacco habit and site of cancer were noted. Data were analyzed by Student's t test and chi-squire (χ2) test. Results: The prevalence of OSCC was significantly (p < 0.001) higher in males (75.9%) than females (24.1%). The mean age of female patients was higher than males (p < 0.001). In both the genders, the buccal mucosa and gingivobuccal sulcus were found to be the most affected sites. Moreover, the smokeless form of tobacco was found to be significantly associated with OSCC, especially in females. Conclusion: The study concluded that OSCC is more common in men as compared to women, probably due to habit of tobacco consumption. Smokeless tobacco use is an important risk factor, especially in females.
format Article
id doaj-art-d8ced91801f34434867d4dc87d141c5a
institution DOAJ
issn 2212-4268
language English
publishDate 2016-01-01
publisher Elsevier
record_format Article
series Journal of Oral Biology and Craniofacial Research
spelling doaj-art-d8ced91801f34434867d4dc87d141c5a2025-08-20T02:50:27ZengElsevierJournal of Oral Biology and Craniofacial Research2212-42682016-01-0161323510.1016/j.jobcr.2015.11.002Clinico-epidemiological study of oral squamous cell carcinoma: A tertiary care centre study in North IndiaMahendra Pratap Singh0Vijay Kumar1Akash Agarwal2Rajendra Kumar3M.L.B. Bhatt4Sanjeev Misra5Department of Surgical Oncology, King George's Medical University, Lucknow, UP, IndiaDepartment of Surgical Oncology, King George's Medical University, Lucknow, UP, IndiaDepartment of Surgical Oncology, Dr. Ram Manohar Lohia Institute of Medical Sciences, Vibhuti Khand, Gomtinagar, Lucknow, UP, IndiaDepartment of Radiotherapy, King George's Medical University, Lucknow, UP, IndiaDepartment of Radiotherapy, King George's Medical University, Lucknow, UP, IndiaDirector, AIIMS, Jodhpur, Rajasthan, India; Department of Surgical Oncology, King George's Medical University, Lucknow, UP, India; Corresponding author.Introduction: Oral squamous cell carcinoma (OSCC) ranks 12th most common cancer in the world. Objective: The aim of this study was to retrospectively evaluate the OSCC. Methods: A retrospective study of 611 OSCC patients from January 2010 to December 2013 was carried out in Department of Surgical Oncology, King George's Medical University, Lucknow, India. Details of patient's sex, age, tobacco habit and site of cancer were noted. Data were analyzed by Student's t test and chi-squire (χ2) test. Results: The prevalence of OSCC was significantly (p < 0.001) higher in males (75.9%) than females (24.1%). The mean age of female patients was higher than males (p < 0.001). In both the genders, the buccal mucosa and gingivobuccal sulcus were found to be the most affected sites. Moreover, the smokeless form of tobacco was found to be significantly associated with OSCC, especially in females. Conclusion: The study concluded that OSCC is more common in men as compared to women, probably due to habit of tobacco consumption. Smokeless tobacco use is an important risk factor, especially in females.http://www.sciencedirect.com/science/article/pii/S2212426815001268Oral squamous cell carcinomaOral cancerCancer of oral cavityHead and neck cancerOSCC
spellingShingle Mahendra Pratap Singh
Vijay Kumar
Akash Agarwal
Rajendra Kumar
M.L.B. Bhatt
Sanjeev Misra
Clinico-epidemiological study of oral squamous cell carcinoma: A tertiary care centre study in North India
Journal of Oral Biology and Craniofacial Research
Oral squamous cell carcinoma
Oral cancer
Cancer of oral cavity
Head and neck cancer
OSCC
title Clinico-epidemiological study of oral squamous cell carcinoma: A tertiary care centre study in North India
title_full Clinico-epidemiological study of oral squamous cell carcinoma: A tertiary care centre study in North India
title_fullStr Clinico-epidemiological study of oral squamous cell carcinoma: A tertiary care centre study in North India
title_full_unstemmed Clinico-epidemiological study of oral squamous cell carcinoma: A tertiary care centre study in North India
title_short Clinico-epidemiological study of oral squamous cell carcinoma: A tertiary care centre study in North India
title_sort clinico epidemiological study of oral squamous cell carcinoma a tertiary care centre study in north india
topic Oral squamous cell carcinoma
Oral cancer
Cancer of oral cavity
Head and neck cancer
OSCC
url http://www.sciencedirect.com/science/article/pii/S2212426815001268
work_keys_str_mv AT mahendrapratapsingh clinicoepidemiologicalstudyoforalsquamouscellcarcinomaatertiarycarecentrestudyinnorthindia
AT vijaykumar clinicoepidemiologicalstudyoforalsquamouscellcarcinomaatertiarycarecentrestudyinnorthindia
AT akashagarwal clinicoepidemiologicalstudyoforalsquamouscellcarcinomaatertiarycarecentrestudyinnorthindia
AT rajendrakumar clinicoepidemiologicalstudyoforalsquamouscellcarcinomaatertiarycarecentrestudyinnorthindia
AT mlbbhatt clinicoepidemiologicalstudyoforalsquamouscellcarcinomaatertiarycarecentrestudyinnorthindia
AT sanjeevmisra clinicoepidemiologicalstudyoforalsquamouscellcarcinomaatertiarycarecentrestudyinnorthindia