Challenges in drug delivery to the tumors—nanoparticles in medicine
Nanotechnology is a relatively young field of science that has found wide application in medicine, especially in oncology. It focuses on studying molecules at the atomic, molecular, and supramolecular levels, enabling the development of innovative therapeutic solutions. Thanks to research in this fi...
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| Format: | Article |
| Language: | English |
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Open Exploration
2025-08-01
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| Series: | Exploration of Drug Science |
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| Online Access: | https://www.explorationpub.com/uploads/Article/A1008126/1008126.pdf |
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| author | Dorota Bartusik-Aebisher Aleksandra Kotlińska Katarzyna Koszarska David Aebisher |
| author_facet | Dorota Bartusik-Aebisher Aleksandra Kotlińska Katarzyna Koszarska David Aebisher |
| author_sort | Dorota Bartusik-Aebisher |
| collection | DOAJ |
| description | Nanotechnology is a relatively young field of science that has found wide application in medicine, especially in oncology. It focuses on studying molecules at the atomic, molecular, and supramolecular levels, enabling the development of innovative therapeutic solutions. Thanks to research in this field, it has become possible to introduce nanoparticles (NPs) into therapy, specially designed molecules that release the drug in a precisely defined place. This approach allows for maintaining the appropriate therapeutic concentration of the drug substance in the body for a longer period of time. The use of NPs in the treatment of cancer diseases helps to overcome the limitations of traditional chemotherapy, such as systemic, toxic effects of drugs, lack of specificity towards cancer cells, and limited bioavailability. NPs can be used not only as drug carriers, but also as contrast agents enabling imaging at the molecular level. More accurate visualization of diseased tissues is possible thanks to the small size of NPs, optical properties, and the ability to accumulate in the tumor area. Additionally, the use of specific ligands allows detection of pathological changes at the cellular level, allowing for earlier detection of changes, which in turn increases the probability of complete recovery of the patient. |
| format | Article |
| id | doaj-art-d8bb5dc0aae2414ba17ca71ba8347c54 |
| institution | Kabale University |
| issn | 2836-7677 |
| language | English |
| publishDate | 2025-08-01 |
| publisher | Open Exploration |
| record_format | Article |
| series | Exploration of Drug Science |
| spelling | doaj-art-d8bb5dc0aae2414ba17ca71ba8347c542025-08-22T08:08:16ZengOpen ExplorationExploration of Drug Science2836-76772025-08-013100812610.37349/eds.2025.1008126Challenges in drug delivery to the tumors—nanoparticles in medicineDorota Bartusik-Aebisher0https://orcid.org/0000-0002-5557-5464Aleksandra Kotlińska1Katarzyna Koszarska2David Aebisher3https://orcid.org/0000-0002-2661-6570Department of Biochemistry and General Chemistry, Faculty of Medicine, Medicum Collegium, University of Rzeszów, 35-959 Rzeszów, PolandStudent Scientific Club URCell, Faculty of Medicine, Medicum Collegium, University of Rzeszów, 35-959 Rzeszów, PolandStudent Scientific Club URCell, Faculty of Medicine, Medicum Collegium, University of Rzeszów, 35-959 Rzeszów, PolandDepartment of Photomedicine and Physical Chemistry, Faculty of Medicine, Medicum Collegium, University of Rzeszów, 35-959 Rzeszów, PolandNanotechnology is a relatively young field of science that has found wide application in medicine, especially in oncology. It focuses on studying molecules at the atomic, molecular, and supramolecular levels, enabling the development of innovative therapeutic solutions. Thanks to research in this field, it has become possible to introduce nanoparticles (NPs) into therapy, specially designed molecules that release the drug in a precisely defined place. This approach allows for maintaining the appropriate therapeutic concentration of the drug substance in the body for a longer period of time. The use of NPs in the treatment of cancer diseases helps to overcome the limitations of traditional chemotherapy, such as systemic, toxic effects of drugs, lack of specificity towards cancer cells, and limited bioavailability. NPs can be used not only as drug carriers, but also as contrast agents enabling imaging at the molecular level. More accurate visualization of diseased tissues is possible thanks to the small size of NPs, optical properties, and the ability to accumulate in the tumor area. Additionally, the use of specific ligands allows detection of pathological changes at the cellular level, allowing for earlier detection of changes, which in turn increases the probability of complete recovery of the patient.https://www.explorationpub.com/uploads/Article/A1008126/1008126.pdfnanotechnologynanoparticlestumorbioavailability |
| spellingShingle | Dorota Bartusik-Aebisher Aleksandra Kotlińska Katarzyna Koszarska David Aebisher Challenges in drug delivery to the tumors—nanoparticles in medicine Exploration of Drug Science nanotechnology nanoparticles tumor bioavailability |
| title | Challenges in drug delivery to the tumors—nanoparticles in medicine |
| title_full | Challenges in drug delivery to the tumors—nanoparticles in medicine |
| title_fullStr | Challenges in drug delivery to the tumors—nanoparticles in medicine |
| title_full_unstemmed | Challenges in drug delivery to the tumors—nanoparticles in medicine |
| title_short | Challenges in drug delivery to the tumors—nanoparticles in medicine |
| title_sort | challenges in drug delivery to the tumors nanoparticles in medicine |
| topic | nanotechnology nanoparticles tumor bioavailability |
| url | https://www.explorationpub.com/uploads/Article/A1008126/1008126.pdf |
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