High Prevalence of Artemisinin-Resistant Plasmodium falciparum, Southeastern Sudan

We conducted a hospital-based cross-sectional study of Plasmodium falciparum in 2017 in southeastern Sudan. Among 257 P. falciparum samples, we found 22% harbored the pfkelch13 R622I mutation and 10.7% showed hrp2/3 gene deletions. Our findings highlight the urgent need for enhanced surveillance of...

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Main Authors: Mariangela L’Episcopia, Albadawi A. Talha, Bakri Y.M. Nour, Ibrahim Mohamed Ahmed Sana, Emmanuelle Caspar, Lucas Thiebaut, Lucien Platon, Buze Chala, Laurence Ma, Lemu Golassa, Edvige Perrotti, Carlo Severini, Didier Menard
Format: Article
Language:English
Published: Centers for Disease Control and Prevention 2025-06-01
Series:Emerging Infectious Diseases
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Online Access:https://wwwnc.cdc.gov/eid/article/31/6/24-1810_article
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author Mariangela L’Episcopia
Albadawi A. Talha
Bakri Y.M. Nour
Ibrahim Mohamed Ahmed Sana
Emmanuelle Caspar
Lucas Thiebaut
Lucien Platon
Buze Chala
Laurence Ma
Lemu Golassa
Edvige Perrotti
Carlo Severini
Didier Menard
author_facet Mariangela L’Episcopia
Albadawi A. Talha
Bakri Y.M. Nour
Ibrahim Mohamed Ahmed Sana
Emmanuelle Caspar
Lucas Thiebaut
Lucien Platon
Buze Chala
Laurence Ma
Lemu Golassa
Edvige Perrotti
Carlo Severini
Didier Menard
author_sort Mariangela L’Episcopia
collection DOAJ
description We conducted a hospital-based cross-sectional study of Plasmodium falciparum in 2017 in southeastern Sudan. Among 257 P. falciparum samples, we found 22% harbored the pfkelch13 R622I mutation and 10.7% showed hrp2/3 gene deletions. Our findings highlight the urgent need for enhanced surveillance of drug- and diagnostic-resistant parasites in the Horn of Africa.
format Article
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institution DOAJ
issn 1080-6040
1080-6059
language English
publishDate 2025-06-01
publisher Centers for Disease Control and Prevention
record_format Article
series Emerging Infectious Diseases
spelling doaj-art-d8aec142d2d14906b6aa3d82361dcf842025-08-20T03:12:42ZengCenters for Disease Control and PreventionEmerging Infectious Diseases1080-60401080-60592025-06-013161211121510.3201/eid3106.241810High Prevalence of Artemisinin-Resistant Plasmodium falciparum, Southeastern SudanMariangela L’EpiscopiaAlbadawi A. TalhaBakri Y.M. NourIbrahim Mohamed Ahmed SanaEmmanuelle CasparLucas ThiebautLucien PlatonBuze ChalaLaurence MaLemu GolassaEdvige PerrottiCarlo SeveriniDidier Menard We conducted a hospital-based cross-sectional study of Plasmodium falciparum in 2017 in southeastern Sudan. Among 257 P. falciparum samples, we found 22% harbored the pfkelch13 R622I mutation and 10.7% showed hrp2/3 gene deletions. Our findings highlight the urgent need for enhanced surveillance of drug- and diagnostic-resistant parasites in the Horn of Africa. https://wwwnc.cdc.gov/eid/article/31/6/24-1810_articlePlasmodium falciparumantimicrobial resistanceArtemisininparasitesSudan
spellingShingle Mariangela L’Episcopia
Albadawi A. Talha
Bakri Y.M. Nour
Ibrahim Mohamed Ahmed Sana
Emmanuelle Caspar
Lucas Thiebaut
Lucien Platon
Buze Chala
Laurence Ma
Lemu Golassa
Edvige Perrotti
Carlo Severini
Didier Menard
High Prevalence of Artemisinin-Resistant Plasmodium falciparum, Southeastern Sudan
Emerging Infectious Diseases
Plasmodium falciparum
antimicrobial resistance
Artemisinin
parasites
Sudan
title High Prevalence of Artemisinin-Resistant Plasmodium falciparum, Southeastern Sudan
title_full High Prevalence of Artemisinin-Resistant Plasmodium falciparum, Southeastern Sudan
title_fullStr High Prevalence of Artemisinin-Resistant Plasmodium falciparum, Southeastern Sudan
title_full_unstemmed High Prevalence of Artemisinin-Resistant Plasmodium falciparum, Southeastern Sudan
title_short High Prevalence of Artemisinin-Resistant Plasmodium falciparum, Southeastern Sudan
title_sort high prevalence of artemisinin resistant plasmodium falciparum southeastern sudan
topic Plasmodium falciparum
antimicrobial resistance
Artemisinin
parasites
Sudan
url https://wwwnc.cdc.gov/eid/article/31/6/24-1810_article
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