Haemodynamics and post-exercise recovery response in COPD-PH and ILD-PH: An appraisal
Background: Chronic lung disease (CLD) from either airway obstruction or parenchymal affections can lead to secondary pulmonary hypertension. It may be interesting to compare the two types of CLD-PH. Methods: Subjects of CLD were first evaluated for the primary category of disease with chest X-ray,...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2025-05-01
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| Series: | Lung India |
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| Online Access: | https://journals.lww.com/10.4103/lungindia.lungindia_213_24 |
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| author | Sayoni Sengupta Parthasarathi Bhattacharyya Aniruddha De Sayanti Karmakar Wrick Chakraborty Dipanjan Saha |
| author_facet | Sayoni Sengupta Parthasarathi Bhattacharyya Aniruddha De Sayanti Karmakar Wrick Chakraborty Dipanjan Saha |
| author_sort | Sayoni Sengupta |
| collection | DOAJ |
| description | Background:
Chronic lung disease (CLD) from either airway obstruction or parenchymal affections can lead to secondary pulmonary hypertension. It may be interesting to compare the two types of CLD-PH.
Methods:
Subjects of CLD were first evaluated for the primary category of disease with chest X-ray, HRCT chest, spirometry, and DLCO (diffusion capacity) and then for the presence of PH through exercise of the institutional clinic-radio-echocardiographic algorithm. Those qualifying as either unmixed restrictive (ILD) or COPD (chronic obstructive airway disease) with PH underwent two-chair test for assessment of post-exercise recovery response. The two groups were compared on available parameters.
Results:
The patients with COPD-PH were significantly older with similar FVC and DLCO compared to ILD-PH. In two-chair test, the maximum pulse rate and the desat-max were significantly worse (108.68 ± 1 5.46 vs 101.33 ± 12.62, P = 0.002, and − 5.68 ± 4.78 vs − 3.71 ± 2.73, P = 0.006) for the ILD-PH patients. The ILD-PH sufferers also demonstrated a lower TAPSE (21.16 ± 3.11 vs 22.59 ± 2.71; P-0.001) and a higher calculated mean pulmonary artery pressure (32.00 ± 7.54 vs 30.64 ± 4.22 vs, P = 0.05) compared to the subjects with COPD-PH. The other right ventricular systolic functional parameters [systolic excursion velocity (S-prime), right ventricular free wall global longitudinal strain, systolic pulmonary arterial pressure, tricuspid regurgitation jet velocity] supported the trend.
Conclusion:
The ILD-PH patients show relatively higher PH with lower right ventricular systolic function than COPD-PH. |
| format | Article |
| id | doaj-art-d8acd8d726fe487da0993fe7f4eb5342 |
| institution | Kabale University |
| issn | 0970-2113 0974-598X |
| language | English |
| publishDate | 2025-05-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Lung India |
| spelling | doaj-art-d8acd8d726fe487da0993fe7f4eb53422025-08-20T03:53:03ZengWolters Kluwer Medknow PublicationsLung India0970-21130974-598X2025-05-0142322523010.4103/lungindia.lungindia_213_24Haemodynamics and post-exercise recovery response in COPD-PH and ILD-PH: An appraisalSayoni SenguptaParthasarathi BhattacharyyaAniruddha DeSayanti KarmakarWrick ChakrabortyDipanjan SahaBackground: Chronic lung disease (CLD) from either airway obstruction or parenchymal affections can lead to secondary pulmonary hypertension. It may be interesting to compare the two types of CLD-PH. Methods: Subjects of CLD were first evaluated for the primary category of disease with chest X-ray, HRCT chest, spirometry, and DLCO (diffusion capacity) and then for the presence of PH through exercise of the institutional clinic-radio-echocardiographic algorithm. Those qualifying as either unmixed restrictive (ILD) or COPD (chronic obstructive airway disease) with PH underwent two-chair test for assessment of post-exercise recovery response. The two groups were compared on available parameters. Results: The patients with COPD-PH were significantly older with similar FVC and DLCO compared to ILD-PH. In two-chair test, the maximum pulse rate and the desat-max were significantly worse (108.68 ± 1 5.46 vs 101.33 ± 12.62, P = 0.002, and − 5.68 ± 4.78 vs − 3.71 ± 2.73, P = 0.006) for the ILD-PH patients. The ILD-PH sufferers also demonstrated a lower TAPSE (21.16 ± 3.11 vs 22.59 ± 2.71; P-0.001) and a higher calculated mean pulmonary artery pressure (32.00 ± 7.54 vs 30.64 ± 4.22 vs, P = 0.05) compared to the subjects with COPD-PH. The other right ventricular systolic functional parameters [systolic excursion velocity (S-prime), right ventricular free wall global longitudinal strain, systolic pulmonary arterial pressure, tricuspid regurgitation jet velocity] supported the trend. Conclusion: The ILD-PH patients show relatively higher PH with lower right ventricular systolic function than COPD-PH.https://journals.lww.com/10.4103/lungindia.lungindia_213_242-chair testchronic lung diseasecopdildpost-exercise recovery responsepulmonary artery pressurepulmonary hypertensionright ventricular systolic dysfunction |
| spellingShingle | Sayoni Sengupta Parthasarathi Bhattacharyya Aniruddha De Sayanti Karmakar Wrick Chakraborty Dipanjan Saha Haemodynamics and post-exercise recovery response in COPD-PH and ILD-PH: An appraisal Lung India 2-chair test chronic lung disease copd ild post-exercise recovery response pulmonary artery pressure pulmonary hypertension right ventricular systolic dysfunction |
| title | Haemodynamics and post-exercise recovery response in COPD-PH and ILD-PH: An appraisal |
| title_full | Haemodynamics and post-exercise recovery response in COPD-PH and ILD-PH: An appraisal |
| title_fullStr | Haemodynamics and post-exercise recovery response in COPD-PH and ILD-PH: An appraisal |
| title_full_unstemmed | Haemodynamics and post-exercise recovery response in COPD-PH and ILD-PH: An appraisal |
| title_short | Haemodynamics and post-exercise recovery response in COPD-PH and ILD-PH: An appraisal |
| title_sort | haemodynamics and post exercise recovery response in copd ph and ild ph an appraisal |
| topic | 2-chair test chronic lung disease copd ild post-exercise recovery response pulmonary artery pressure pulmonary hypertension right ventricular systolic dysfunction |
| url | https://journals.lww.com/10.4103/lungindia.lungindia_213_24 |
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