Methadone-Induced Toxic Brain Damage

A 29-year-old man presented with comatose after methadone intoxication. Cerebral tomography only showed cortico-subcortical hypodense signal in the right cerebellar hemisphere. Brain MRI showed a rare imaging of FLAIR and DWI hyperintensities in the two cerebellar hemispheres as well as basal gangli...

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Main Authors: Jérôme Corré, Jérôme Pillot, Gilles Hilbert
Format: Article
Language:English
Published: Wiley 2013-01-01
Series:Case Reports in Radiology
Online Access:http://dx.doi.org/10.1155/2013/602981
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author Jérôme Corré
Jérôme Pillot
Gilles Hilbert
author_facet Jérôme Corré
Jérôme Pillot
Gilles Hilbert
author_sort Jérôme Corré
collection DOAJ
description A 29-year-old man presented with comatose after methadone intoxication. Cerebral tomography only showed cortico-subcortical hypodense signal in the right cerebellar hemisphere. Brain MRI showed a rare imaging of FLAIR and DWI hyperintensities in the two cerebellar hemispheres as well as basal ganglia (globi pallidi), compatible with methadone overdose. To our knowledge this is the first reported case of both cerebellar and basal ganglia involvement in methadone overdose.
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institution Kabale University
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publishDate 2013-01-01
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series Case Reports in Radiology
spelling doaj-art-d8a575161cf5429c81c05874054207122025-02-03T01:00:09ZengWileyCase Reports in Radiology2090-68622090-68702013-01-01201310.1155/2013/602981602981Methadone-Induced Toxic Brain DamageJérôme Corré0Jérôme Pillot1Gilles Hilbert2Medical Intensive Care Unit, Bordeaux University Hospital, Pellegrin Hospital, 33000 Bordeaux, FranceMedical Intensive Care Unit, Bordeaux University Hospital, Pellegrin Hospital, 33000 Bordeaux, FranceMedical Intensive Care Unit, Bordeaux University Hospital, Pellegrin Hospital, 33000 Bordeaux, FranceA 29-year-old man presented with comatose after methadone intoxication. Cerebral tomography only showed cortico-subcortical hypodense signal in the right cerebellar hemisphere. Brain MRI showed a rare imaging of FLAIR and DWI hyperintensities in the two cerebellar hemispheres as well as basal ganglia (globi pallidi), compatible with methadone overdose. To our knowledge this is the first reported case of both cerebellar and basal ganglia involvement in methadone overdose.http://dx.doi.org/10.1155/2013/602981
spellingShingle Jérôme Corré
Jérôme Pillot
Gilles Hilbert
Methadone-Induced Toxic Brain Damage
Case Reports in Radiology
title Methadone-Induced Toxic Brain Damage
title_full Methadone-Induced Toxic Brain Damage
title_fullStr Methadone-Induced Toxic Brain Damage
title_full_unstemmed Methadone-Induced Toxic Brain Damage
title_short Methadone-Induced Toxic Brain Damage
title_sort methadone induced toxic brain damage
url http://dx.doi.org/10.1155/2013/602981
work_keys_str_mv AT jeromecorre methadoneinducedtoxicbraindamage
AT jeromepillot methadoneinducedtoxicbraindamage
AT gilleshilbert methadoneinducedtoxicbraindamage