A nucleolus-predominant piggyBac transposase, NP-mPB, mediates elevated transposition efficiency in mammalian cells.

A nucleolus-predominant piggyBac transposase, NP-mPB, mediates elevated transposition efficiency in mammalian cells.

PiggyBac is a prevalent transposon system used to deliver transgenes and functionally explore the mammalian untouched genomic territory. The important features of piggyBac transposon are the relatively low insertion site preference and the ability of seamless removal from genome, which allow its pot...

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Bibliographic Details
Main Authors: Jin-Bon Hong, Fu-Ju Chou, Amy T Ku, Hsiang-Hsuan Fan, Tung-Lung Lee, Yung-Hsin Huang, Tsung-Lin Yang, I-Chang Su, I-Shing Yu, Shu-Wha Lin, Chung-Liang Chien, Hong-Nerng Ho, You-Tzung Chen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0089396&type=printable
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