Ornidazole-induced involuntary tremor in a Chinese woman: a rare case report and literature review
Abstract Nitromidazole antibiotics, exemplified by metronidazole and ornidazole, have been reported to trigger a spectrum of adverse effects. These encompass ataxia, hearing loss, visual impairment, psychomotor dysfunction, intellectual impairment, and epileptic seizures (Rinsho Shinkeigaku 64:637-6...
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| Format: | Article |
| Language: | English |
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BMC
2025-07-01
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| Series: | BMC Neurology |
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| Online Access: | https://doi.org/10.1186/s12883-025-04316-z |
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| author | Hui Wang Yanling Huang Xuefei Wang Fulan Yang Chunjing Jiang Yueqin Zhou Liu Yang |
| author_facet | Hui Wang Yanling Huang Xuefei Wang Fulan Yang Chunjing Jiang Yueqin Zhou Liu Yang |
| author_sort | Hui Wang |
| collection | DOAJ |
| description | Abstract Nitromidazole antibiotics, exemplified by metronidazole and ornidazole, have been reported to trigger a spectrum of adverse effects. These encompass ataxia, hearing loss, visual impairment, psychomotor dysfunction, intellectual impairment, and epileptic seizures (Rinsho Shinkeigaku 64:637-641, 2024). Nevertheless, cases of involuntary limb tremors have been scarcely documented. Ornidazole, the most recent derivative within this class, boasts a longer half - life and is infrequently linked to limb tremors. This article reports a 63-year-old female patient who developed progressive limb tremors following long-term, high-dose administration of ornidazole, with symptoms gradually alleviating after discontinuation of the drug. |
| format | Article |
| id | doaj-art-d89fc22356e541fd9b9b8944256d85a0 |
| institution | Kabale University |
| issn | 1471-2377 |
| language | English |
| publishDate | 2025-07-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Neurology |
| spelling | doaj-art-d89fc22356e541fd9b9b8944256d85a02025-08-20T04:02:55ZengBMCBMC Neurology1471-23772025-07-012511510.1186/s12883-025-04316-zOrnidazole-induced involuntary tremor in a Chinese woman: a rare case report and literature reviewHui Wang0Yanling Huang1Xuefei Wang2Fulan Yang3Chunjing Jiang4Yueqin Zhou5Liu Yang6Department of Neurology, Chongqing University Central Hospi tal (Chongqing Emergency Medical Center)Department of Neurology, Chongqing University Central Hospi tal (Chongqing Emergency Medical Center)Department of Neurology, Chongqing University Central Hospi tal (Chongqing Emergency Medical Center)Department of Neurology, Chongqing University Central Hospi tal (Chongqing Emergency Medical Center)Department of Neurology, Chongqing University Central Hospi tal (Chongqing Emergency Medical Center)Department of Neurology, Chongqing University Central Hospi tal (Chongqing Emergency Medical Center)Department of Neurology, Chongqing University Central Hospi tal (Chongqing Emergency Medical Center)Abstract Nitromidazole antibiotics, exemplified by metronidazole and ornidazole, have been reported to trigger a spectrum of adverse effects. These encompass ataxia, hearing loss, visual impairment, psychomotor dysfunction, intellectual impairment, and epileptic seizures (Rinsho Shinkeigaku 64:637-641, 2024). Nevertheless, cases of involuntary limb tremors have been scarcely documented. Ornidazole, the most recent derivative within this class, boasts a longer half - life and is infrequently linked to limb tremors. This article reports a 63-year-old female patient who developed progressive limb tremors following long-term, high-dose administration of ornidazole, with symptoms gradually alleviating after discontinuation of the drug.https://doi.org/10.1186/s12883-025-04316-zOrnidazoleTremorsMRI |
| spellingShingle | Hui Wang Yanling Huang Xuefei Wang Fulan Yang Chunjing Jiang Yueqin Zhou Liu Yang Ornidazole-induced involuntary tremor in a Chinese woman: a rare case report and literature review BMC Neurology Ornidazole Tremors MRI |
| title | Ornidazole-induced involuntary tremor in a Chinese woman: a rare case report and literature review |
| title_full | Ornidazole-induced involuntary tremor in a Chinese woman: a rare case report and literature review |
| title_fullStr | Ornidazole-induced involuntary tremor in a Chinese woman: a rare case report and literature review |
| title_full_unstemmed | Ornidazole-induced involuntary tremor in a Chinese woman: a rare case report and literature review |
| title_short | Ornidazole-induced involuntary tremor in a Chinese woman: a rare case report and literature review |
| title_sort | ornidazole induced involuntary tremor in a chinese woman a rare case report and literature review |
| topic | Ornidazole Tremors MRI |
| url | https://doi.org/10.1186/s12883-025-04316-z |
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