Perfomance analysis of a small animal PET scanner using 68Ga Isotope

In recent years, the use of PET scanners for small animals in preclinical research has been growing in Brazil, due to this fact it is essential to have a quality assurance program to ensure the good performance of these scanners or indicate the need for corrective maintenance. In 2008, the National...

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Main Authors: Victória Garcia Moreira, Anna Clara Moreira Silva, Rodrigo Modesto Gadelha Gontijo, Andréa Vidal Ferreira
Format: Article
Language:English
Published: Brazilian Radiation Protection Society (Sociedade Brasileira de Proteção Radiológica, SBPR) 2025-06-01
Series:Brazilian Journal of Radiation Sciences
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Online Access:https://bjrs.org.br/revista/index.php/REVISTA/article/view/2844
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author Victória Garcia Moreira
Anna Clara Moreira Silva
Rodrigo Modesto Gadelha Gontijo
Andréa Vidal Ferreira
author_facet Victória Garcia Moreira
Anna Clara Moreira Silva
Rodrigo Modesto Gadelha Gontijo
Andréa Vidal Ferreira
author_sort Victória Garcia Moreira
collection DOAJ
description In recent years, the use of PET scanners for small animals in preclinical research has been growing in Brazil, due to this fact it is essential to have a quality assurance program to ensure the good performance of these scanners or indicate the need for corrective maintenance. In 2008, the National Association of Electrical Equipment Manufacturers (NEMA) in the USA published a document that proposes the following tests to ensure quality control: uniformity, spill-over ratio, and recovery coefficients. Thus, the objective of this work was to evaluate the image quality of the PET scanner for small animals LabPET SOLO 4 using the isotope Gallium-68. The results revealed that the use of the isotope 68Ga was quite different from standard tests using 18F. The project provided us with a comprehensive understanding of the functioning of the PET scanner when employing the radionuclide 68Ga. This evaluation is of crucial relevance for application in laboratories, especially in the quantitative analysis of PET images and in the planning of preclinical studies
format Article
id doaj-art-d896fe14455d4a2099d683f09a64f2e3
institution DOAJ
issn 2319-0612
language English
publishDate 2025-06-01
publisher Brazilian Radiation Protection Society (Sociedade Brasileira de Proteção Radiológica, SBPR)
record_format Article
series Brazilian Journal of Radiation Sciences
spelling doaj-art-d896fe14455d4a2099d683f09a64f2e32025-08-20T03:12:31ZengBrazilian Radiation Protection Society (Sociedade Brasileira de Proteção Radiológica, SBPR)Brazilian Journal of Radiation Sciences2319-06122025-06-0113210.15392/2319-0612.2025.28442469Perfomance analysis of a small animal PET scanner using 68Ga IsotopeVictória Garcia Moreira0Anna Clara Moreira Silva1Rodrigo Modesto Gadelha Gontijo2Andréa Vidal Ferreira3Universidade Federal de Minas Gerais UFMG, Faculdade de Medicina, Departamento de Anatomia e ImagemUniversidade Federal de Minas Gerais UFMG, Faculdade de Medicina, Departamento de Anatomia e ImagemEmpresa Brasileira de Serviços Hospitalares EBSERH-HC/UFMGCentro de Desenvolvimento da Tecnologia Nuclear CDTN/CNEN 31.270-901, Belo Horizonte, Minas Gerais, Brazil In recent years, the use of PET scanners for small animals in preclinical research has been growing in Brazil, due to this fact it is essential to have a quality assurance program to ensure the good performance of these scanners or indicate the need for corrective maintenance. In 2008, the National Association of Electrical Equipment Manufacturers (NEMA) in the USA published a document that proposes the following tests to ensure quality control: uniformity, spill-over ratio, and recovery coefficients. Thus, the objective of this work was to evaluate the image quality of the PET scanner for small animals LabPET SOLO 4 using the isotope Gallium-68. The results revealed that the use of the isotope 68Ga was quite different from standard tests using 18F. The project provided us with a comprehensive understanding of the functioning of the PET scanner when employing the radionuclide 68Ga. This evaluation is of crucial relevance for application in laboratories, especially in the quantitative analysis of PET images and in the planning of preclinical studies https://bjrs.org.br/revista/index.php/REVISTA/article/view/2844PETgalium-68Image Quality
spellingShingle Victória Garcia Moreira
Anna Clara Moreira Silva
Rodrigo Modesto Gadelha Gontijo
Andréa Vidal Ferreira
Perfomance analysis of a small animal PET scanner using 68Ga Isotope
Brazilian Journal of Radiation Sciences
PET
galium-68
Image Quality
title Perfomance analysis of a small animal PET scanner using 68Ga Isotope
title_full Perfomance analysis of a small animal PET scanner using 68Ga Isotope
title_fullStr Perfomance analysis of a small animal PET scanner using 68Ga Isotope
title_full_unstemmed Perfomance analysis of a small animal PET scanner using 68Ga Isotope
title_short Perfomance analysis of a small animal PET scanner using 68Ga Isotope
title_sort perfomance analysis of a small animal pet scanner using 68ga isotope
topic PET
galium-68
Image Quality
url https://bjrs.org.br/revista/index.php/REVISTA/article/view/2844
work_keys_str_mv AT victoriagarciamoreira perfomanceanalysisofasmallanimalpetscannerusing68gaisotope
AT annaclaramoreirasilva perfomanceanalysisofasmallanimalpetscannerusing68gaisotope
AT rodrigomodestogadelhagontijo perfomanceanalysisofasmallanimalpetscannerusing68gaisotope
AT andreavidalferreira perfomanceanalysisofasmallanimalpetscannerusing68gaisotope