Prevalence of fatigue and perceived fatigability in older adults: a systematic review and meta-analysis

Abstract Fatigue is a common health complaint in older adults, but its prevalence varies widely among studies due to differences in populations and assessment tools. The objective of this review is to systematically evaluate the prevalence of fatigue and perceived fatigability in older adults with P...

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Main Authors: Ting Hu, Feiling Wang, Qiuchen Duan, Xueyang Zhao, Fen Yang
Format: Article
Language:English
Published: Nature Portfolio 2025-02-01
Series:Scientific Reports
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Online Access:https://doi.org/10.1038/s41598-025-88961-x
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author Ting Hu
Feiling Wang
Qiuchen Duan
Xueyang Zhao
Fen Yang
author_facet Ting Hu
Feiling Wang
Qiuchen Duan
Xueyang Zhao
Fen Yang
author_sort Ting Hu
collection DOAJ
description Abstract Fatigue is a common health complaint in older adults, but its prevalence varies widely among studies due to differences in populations and assessment tools. The objective of this review is to systematically evaluate the prevalence of fatigue and perceived fatigability in older adults with PRISMA 2020. Four databases—PubMed, Embase, Web of Science (WoS), and Cochrane Library—were systematically searched as of December 27, 2023. Cochrane Q tests and the I 2 statistic were used using Stata16.0 to assess between-study heterogeneity. A total of 21 studies involving 17843 participants were included in this study. The prevalence of fatigue in older adults was 42.6%, and the prevalence of perceived physical fatigability and mental fatigability was 58.2% and 24.0%. Meta-analysis showed that the prevalence of perceived physical fatigability among older adults was very high. This prevalence varied with regional economic development level, age of the subjects, sample size, and representativeness of the subjects. Fatigue is a health dilemma faced by most older adults. To improve quality of life, early and regular fatigue assessment should be part of routine health screening for older adults.
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spelling doaj-art-d89006b4355048b198855bbabc13dee02025-02-09T12:30:03ZengNature PortfolioScientific Reports2045-23222025-02-0115111110.1038/s41598-025-88961-xPrevalence of fatigue and perceived fatigability in older adults: a systematic review and meta-analysisTing Hu0Feiling Wang1Qiuchen Duan2Xueyang Zhao3Fen Yang4Nursing Department, Sir Run Run Shaw Hospital, Zhejiang University School of MedicineNursing Department, Sir Run Run Shaw Hospital, Zhejiang University School of MedicineTong Ji Hospital Tong Ji Medical College Hua Zhong University of Science & TechnologyNingbo Municipal Hospital of Traditional Chinese Medicine (TCM), Affiliated Hospital of Zhejiang Chinese Medical UniversityHubei University of Chinese MedicineAbstract Fatigue is a common health complaint in older adults, but its prevalence varies widely among studies due to differences in populations and assessment tools. The objective of this review is to systematically evaluate the prevalence of fatigue and perceived fatigability in older adults with PRISMA 2020. Four databases—PubMed, Embase, Web of Science (WoS), and Cochrane Library—were systematically searched as of December 27, 2023. Cochrane Q tests and the I 2 statistic were used using Stata16.0 to assess between-study heterogeneity. A total of 21 studies involving 17843 participants were included in this study. The prevalence of fatigue in older adults was 42.6%, and the prevalence of perceived physical fatigability and mental fatigability was 58.2% and 24.0%. Meta-analysis showed that the prevalence of perceived physical fatigability among older adults was very high. This prevalence varied with regional economic development level, age of the subjects, sample size, and representativeness of the subjects. Fatigue is a health dilemma faced by most older adults. To improve quality of life, early and regular fatigue assessment should be part of routine health screening for older adults.https://doi.org/10.1038/s41598-025-88961-xFatigueFrail elderlyMeta-analysisPrevalenceSystematic review
spellingShingle Ting Hu
Feiling Wang
Qiuchen Duan
Xueyang Zhao
Fen Yang
Prevalence of fatigue and perceived fatigability in older adults: a systematic review and meta-analysis
Scientific Reports
Fatigue
Frail elderly
Meta-analysis
Prevalence
Systematic review
title Prevalence of fatigue and perceived fatigability in older adults: a systematic review and meta-analysis
title_full Prevalence of fatigue and perceived fatigability in older adults: a systematic review and meta-analysis
title_fullStr Prevalence of fatigue and perceived fatigability in older adults: a systematic review and meta-analysis
title_full_unstemmed Prevalence of fatigue and perceived fatigability in older adults: a systematic review and meta-analysis
title_short Prevalence of fatigue and perceived fatigability in older adults: a systematic review and meta-analysis
title_sort prevalence of fatigue and perceived fatigability in older adults a systematic review and meta analysis
topic Fatigue
Frail elderly
Meta-analysis
Prevalence
Systematic review
url https://doi.org/10.1038/s41598-025-88961-x
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AT qiuchenduan prevalenceoffatigueandperceivedfatigabilityinolderadultsasystematicreviewandmetaanalysis
AT xueyangzhao prevalenceoffatigueandperceivedfatigabilityinolderadultsasystematicreviewandmetaanalysis
AT fenyang prevalenceoffatigueandperceivedfatigabilityinolderadultsasystematicreviewandmetaanalysis