A glutamine metabolism gene signature with prognostic and predictive value for colorectal cancer survival and immunotherapy response

A glutamine metabolism gene signature with prognostic and predictive value for colorectal cancer survival and immunotherapy response

BackgroundColorectal cancer (CRC) remains a major cause of cancer mortality, and dysregulated glutamine metabolism has emerged as a potential therapeutic target. However, the precise role of glutamine in CRC progression and treatment response remains debated.MethodsThe authors collected transcriptom...

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Bibliographic Details
Main Authors: Yinmeng Zhang, He Zhu, Jiawei Fan, Jiahui Zhao, Yan Xia, Nan Zhang, Hong Xu
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-05-01
Series:Frontiers in Molecular Biosciences
Subjects:
colorectal cancer
glutamine metabolism
microbiome
tumor microenvironment
prognosis
Online Access:https://www.frontiersin.org/articles/10.3389/fmolb.2025.1599141/full
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