Metastatic Melanoma of the Gallbladder in an Asymptomatic Patient

Malignant Melanoma (MM) is among the most dangerous malignancies with some of the least known survival rates. Melanoma most commonly metastasizes to regional lymph nodes, the lungs, and brain. Metastatic disease of the gallbladder (GB) is exceptionally rare making it difficult to diagnose. The fact...

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Main Authors: Asad Khan, Sejal Patel, Daniel J. Zaccarini, Mary McGrath
Format: Article
Language:English
Published: Wiley 2017-01-01
Series:Case Reports in Gastrointestinal Medicine
Online Access:http://dx.doi.org/10.1155/2017/1767418
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author Asad Khan
Sejal Patel
Daniel J. Zaccarini
Mary McGrath
author_facet Asad Khan
Sejal Patel
Daniel J. Zaccarini
Mary McGrath
author_sort Asad Khan
collection DOAJ
description Malignant Melanoma (MM) is among the most dangerous malignancies with some of the least known survival rates. Melanoma most commonly metastasizes to regional lymph nodes, the lungs, and brain. Metastatic disease of the gallbladder (GB) is exceptionally rare making it difficult to diagnose. The fact that typically patients do not present until they are symptomatic—only after widespread metastatic disease has already occurred—is further complicating the diagnosis of MM of the GB. For this reason, MM of the GB is rarely discovered in living patients. In fact, review of the literature showed only 40 instances in which metastatic disease of the GB was reported in living patients. We describe the presentation and management of a patient who had metastatic disease of the GB. However, our case is unique because his malignancy was discovered incidentally while he was asymptomatic. He was successfully treated with an open cholecystectomy. We have presented this case in order to make the necessity of meticulous investigation of potential metastasis in patients with a known history of cutaneous melanoma clear.
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spelling doaj-art-d882abbd8ccf44449f3b613fd23ec6c42025-08-20T03:23:51ZengWileyCase Reports in Gastrointestinal Medicine2090-65282090-65362017-01-01201710.1155/2017/17674181767418Metastatic Melanoma of the Gallbladder in an Asymptomatic PatientAsad Khan0Sejal Patel1Daniel J. Zaccarini2Mary McGrath3SUNY Upstate Medical University, Syracuse, NY 13210, USADepartment of Radiology, SUNY Upstate Medical University, Syracuse, NY 13210, USADepartment of Pathology, SUNY Upstate Medical University, Syracuse, NY 13210, USADepartment of Nuclear Medicine, SUNY Upstate Medical University, Syracuse, NY 13210, USAMalignant Melanoma (MM) is among the most dangerous malignancies with some of the least known survival rates. Melanoma most commonly metastasizes to regional lymph nodes, the lungs, and brain. Metastatic disease of the gallbladder (GB) is exceptionally rare making it difficult to diagnose. The fact that typically patients do not present until they are symptomatic—only after widespread metastatic disease has already occurred—is further complicating the diagnosis of MM of the GB. For this reason, MM of the GB is rarely discovered in living patients. In fact, review of the literature showed only 40 instances in which metastatic disease of the GB was reported in living patients. We describe the presentation and management of a patient who had metastatic disease of the GB. However, our case is unique because his malignancy was discovered incidentally while he was asymptomatic. He was successfully treated with an open cholecystectomy. We have presented this case in order to make the necessity of meticulous investigation of potential metastasis in patients with a known history of cutaneous melanoma clear.http://dx.doi.org/10.1155/2017/1767418
spellingShingle Asad Khan
Sejal Patel
Daniel J. Zaccarini
Mary McGrath
Metastatic Melanoma of the Gallbladder in an Asymptomatic Patient
Case Reports in Gastrointestinal Medicine
title Metastatic Melanoma of the Gallbladder in an Asymptomatic Patient
title_full Metastatic Melanoma of the Gallbladder in an Asymptomatic Patient
title_fullStr Metastatic Melanoma of the Gallbladder in an Asymptomatic Patient
title_full_unstemmed Metastatic Melanoma of the Gallbladder in an Asymptomatic Patient
title_short Metastatic Melanoma of the Gallbladder in an Asymptomatic Patient
title_sort metastatic melanoma of the gallbladder in an asymptomatic patient
url http://dx.doi.org/10.1155/2017/1767418
work_keys_str_mv AT asadkhan metastaticmelanomaofthegallbladderinanasymptomaticpatient
AT sejalpatel metastaticmelanomaofthegallbladderinanasymptomaticpatient
AT danieljzaccarini metastaticmelanomaofthegallbladderinanasymptomaticpatient
AT marymcgrath metastaticmelanomaofthegallbladderinanasymptomaticpatient