Evaluation of Vaccination Status, Awareness, and Seroprevalence of Hepatitis B Virus Infection among Female Sex Workers in Jos

Study’s Excerpt/Novelty • This study is the first to systematically evaluate the immunization status, awareness, and seroprevalence of hepatitis B virus (HBV) infection specifically among female sex workers in Jos, Nigeria, highlighting a significant gap in the existing literature. • It reveals a...

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Main Authors: Hashimu Zakari, Adaobi Vivian Okafor, Y Abubakar Ajang, Jude Y Nkup, Ramman Selvyat Katnap
Format: Article
Language:English
Published: Umaru Musa Yar'adua University, Katsina, Nigeria 2024-06-01
Series:UMYU Journal of Microbiology Research
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Online Access:https://ujmr.umyu.edu.ng/index.php/ujmr/article/view/489
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author Hashimu Zakari
Adaobi Vivian Okafor
Y Abubakar Ajang
Jude Y Nkup
Ramman Selvyat Katnap
author_facet Hashimu Zakari
Adaobi Vivian Okafor
Y Abubakar Ajang
Jude Y Nkup
Ramman Selvyat Katnap
author_sort Hashimu Zakari
collection DOAJ
description Study’s Excerpt/Novelty • This study is the first to systematically evaluate the immunization status, awareness, and seroprevalence of hepatitis B virus (HBV) infection specifically among female sex workers in Jos, Nigeria, highlighting a significant gap in the existing literature. • It reveals a high HBV prevalence rate of 24.4% within this population, with critical insights into demographic variations such as age, marital status, and educational level. • The findings underscore an urgent need for targeted vaccination programs, given the alarmingly low immunization coverage, with only 10.5% of participants fully vaccinated against HBV. Full Abstract The hepatitis B virus (HBV) is the cause of hepatitis B infection, which can lead to malignancy and chronic liver cirrhosis.  There is a dearth of research on the incidence of HBV among Nigerian women who work as sex workers despite the country being characterized as an endemic zone with prevalence among different occupational groups.  The study evaluates the immunization status, awareness of the virus, and seroprevalence and predictors of hepatitis B virus infection among female sex workers.  A descriptive cross-sectional study including 86 female sex workers in Jos brothels was conducted.  Blood samples were collected using the RecombiLISAHbsAg ELISA kit (CTK Biotech Inc., San Diego, USA) to qualitatively detect HBsAg.Twenty (21) out of the 86 subjects tested positive, yielding a 24.4% prevalence rate.  The highest prevalence was found among women in the 36–40 age range (40%), while the lowest (0.0%) was found among those in the age group <20 years.  Married sex workers recorded the highest prevalence of 50%, while separated/divorced recorded the lowest prevalence of 10.0%.  Also, female sex workers without a formal education had the highest prevalence of 66.7%. In comparison, the lowest prevalence of 0.0% was found among those with tertiary education. Those who engaged in sex work for less than five years had the highest prevalence of 30.8%, while the lowest was recorded among those who had five years and above in the sex trade, with a prevalence rate of 0.0%.  There was no statistically significant correlation seen between these high percentages and HBV infection.  Out of the 86 female sex workers, only 9 had received all three doses of the immunization.  This high frequency of vaccine-preventable illness is intolerable; therefore, immunizing this high-risk HBV reservoir population should be justified
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publishDate 2024-06-01
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spelling doaj-art-d86e8d8e046444f49f688912748f77c92024-11-27T17:02:16ZengUmaru Musa Yar'adua University, Katsina, NigeriaUMYU Journal of Microbiology Research2616-06682814-18222024-06-019117318110.47430/ujmr.2491.019489Evaluation of Vaccination Status, Awareness, and Seroprevalence of Hepatitis B Virus Infection among Female Sex Workers in JosHashimu Zakari0https://orcid.org/0009-0005-2021-8263Adaobi Vivian Okafor1https://orcid.org/0009-0000-1070-3138Y Abubakar Ajang2https://orcid.org/0000-0001-6134-5422Jude Y Nkup3https://orcid.org/0000-0001-8609-8384Ramman Selvyat Katnap4https://orcid.org/0000-0001-5593-7544Department of Microbiology, Faculty of Natural Sciences University of Jos, NigeriaDepartment of Microbiology, Faculty of Natural Sciences University of Jos, NigeriaDepartment of Microbiology, Faculty of Natural Sciences University of Jos, NigeriaDepartment of Microbiology, Faculty of Natural Sciences University of Jos, NigeriaDepartment of Microbiology, Faculty of Natural Sciences University of Jos, NigeriaStudy’s Excerpt/Novelty • This study is the first to systematically evaluate the immunization status, awareness, and seroprevalence of hepatitis B virus (HBV) infection specifically among female sex workers in Jos, Nigeria, highlighting a significant gap in the existing literature. • It reveals a high HBV prevalence rate of 24.4% within this population, with critical insights into demographic variations such as age, marital status, and educational level. • The findings underscore an urgent need for targeted vaccination programs, given the alarmingly low immunization coverage, with only 10.5% of participants fully vaccinated against HBV. Full Abstract The hepatitis B virus (HBV) is the cause of hepatitis B infection, which can lead to malignancy and chronic liver cirrhosis.  There is a dearth of research on the incidence of HBV among Nigerian women who work as sex workers despite the country being characterized as an endemic zone with prevalence among different occupational groups.  The study evaluates the immunization status, awareness of the virus, and seroprevalence and predictors of hepatitis B virus infection among female sex workers.  A descriptive cross-sectional study including 86 female sex workers in Jos brothels was conducted.  Blood samples were collected using the RecombiLISAHbsAg ELISA kit (CTK Biotech Inc., San Diego, USA) to qualitatively detect HBsAg.Twenty (21) out of the 86 subjects tested positive, yielding a 24.4% prevalence rate.  The highest prevalence was found among women in the 36–40 age range (40%), while the lowest (0.0%) was found among those in the age group <20 years.  Married sex workers recorded the highest prevalence of 50%, while separated/divorced recorded the lowest prevalence of 10.0%.  Also, female sex workers without a formal education had the highest prevalence of 66.7%. In comparison, the lowest prevalence of 0.0% was found among those with tertiary education. Those who engaged in sex work for less than five years had the highest prevalence of 30.8%, while the lowest was recorded among those who had five years and above in the sex trade, with a prevalence rate of 0.0%.  There was no statistically significant correlation seen between these high percentages and HBV infection.  Out of the 86 female sex workers, only 9 had received all three doses of the immunization.  This high frequency of vaccine-preventable illness is intolerable; therefore, immunizing this high-risk HBV reservoir population should be justifiedhttps://ujmr.umyu.edu.ng/index.php/ujmr/article/view/489seroprevalencehepatitis bfemale sex workerselisa
spellingShingle Hashimu Zakari
Adaobi Vivian Okafor
Y Abubakar Ajang
Jude Y Nkup
Ramman Selvyat Katnap
Evaluation of Vaccination Status, Awareness, and Seroprevalence of Hepatitis B Virus Infection among Female Sex Workers in Jos
UMYU Journal of Microbiology Research
seroprevalence
hepatitis b
female sex workers
elisa
title Evaluation of Vaccination Status, Awareness, and Seroprevalence of Hepatitis B Virus Infection among Female Sex Workers in Jos
title_full Evaluation of Vaccination Status, Awareness, and Seroprevalence of Hepatitis B Virus Infection among Female Sex Workers in Jos
title_fullStr Evaluation of Vaccination Status, Awareness, and Seroprevalence of Hepatitis B Virus Infection among Female Sex Workers in Jos
title_full_unstemmed Evaluation of Vaccination Status, Awareness, and Seroprevalence of Hepatitis B Virus Infection among Female Sex Workers in Jos
title_short Evaluation of Vaccination Status, Awareness, and Seroprevalence of Hepatitis B Virus Infection among Female Sex Workers in Jos
title_sort evaluation of vaccination status awareness and seroprevalence of hepatitis b virus infection among female sex workers in jos
topic seroprevalence
hepatitis b
female sex workers
elisa
url https://ujmr.umyu.edu.ng/index.php/ujmr/article/view/489
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