Clinical and microbiological evaluation of dental plaque on topical application of olive oil, olive oil with 35% Curcuma zedoaria, and olive oil with 30% Azadirachta indica in hospitalized children: A randomized control trial

Background: Hospitalized children find difficulty in performing regular oral hygiene procedures. In such cases, direct application of herbal oils such as olive oil, Azadirachta indica (AI) (neem), and Curcuma zedoaria (CZ) (white turmeric) as antiplaque agents could be beneficial in maintaining oral...

Full description

Saved in:
Bibliographic Details
Main Authors: Anshula Deshpande, Simron Baishya, Sneha Dori, Medha Wadhwa, Khushali Shah
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2025-04-01
Series:Journal of Indian Society of Pedodontics and Preventive Dentistry
Subjects:
Online Access:https://journals.lww.com/10.4103/jisppd.jisppd_68_25
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1849420324820484096
author Anshula Deshpande
Simron Baishya
Sneha Dori
Medha Wadhwa
Khushali Shah
author_facet Anshula Deshpande
Simron Baishya
Sneha Dori
Medha Wadhwa
Khushali Shah
author_sort Anshula Deshpande
collection DOAJ
description Background: Hospitalized children find difficulty in performing regular oral hygiene procedures. In such cases, direct application of herbal oils such as olive oil, Azadirachta indica (AI) (neem), and Curcuma zedoaria (CZ) (white turmeric) as antiplaque agents could be beneficial in maintaining oral hygiene. Aim: The aim of the study was to evaluate the efficacy of normal saline, extra virgin olive oil (EVOO), EVOO with 35% CZ, and EVOO with 30% AI on dental plaque and the count of Streptococcus mutans, Lactobacillus, and Candida albicans in hospitalized children. Settings and Design: This was a randomized control trial. Materials and Methods: 84 hospitalized children of age group 3–14 years were randomly divided by computer-generated random allocation into Group A-EVOO, Group B-EVOO + 35% CZ, Group C-EVOO + 30% AI, and Group D-normal saline with 21 participants in each group and applied with sterile gauze. The plaque score was recorded and analyzed by Loe and Silness plaque index. In addition, plaque sample for microbial analysis was collected from buccal/lingual surfaces, and CFU count was measured at baseline, 24 h, 48 h, and 72 h. Results: The four groups showed a reduction in plaque score and CFU counts from baseline to 72 h with P < 0.05 indicating a statistically significant difference. Group C has shown significant antimicrobial activity against Group A, Group B, and Group D (P = 0.0001) at 72 h. Conclusion: EVOO + 35% CZ showed the best treatment outcome in the reduction of microbial count followed by EVOO + 30% AI and EVOO. All the preparations including normal saline have antiplaque properties with the best outcome achieved in EVOO + 35% CZ and EVOO + 30% AI preparations.
format Article
id doaj-art-d86df0f5c21149858cae84be37c7d3dd
institution Kabale University
issn 0970-4388
1998-3905
language English
publishDate 2025-04-01
publisher Wolters Kluwer Medknow Publications
record_format Article
series Journal of Indian Society of Pedodontics and Preventive Dentistry
spelling doaj-art-d86df0f5c21149858cae84be37c7d3dd2025-08-20T03:31:47ZengWolters Kluwer Medknow PublicationsJournal of Indian Society of Pedodontics and Preventive Dentistry0970-43881998-39052025-04-0143223624310.4103/jisppd.jisppd_68_25Clinical and microbiological evaluation of dental plaque on topical application of olive oil, olive oil with 35% Curcuma zedoaria, and olive oil with 30% Azadirachta indica in hospitalized children: A randomized control trialAnshula DeshpandeSimron BaishyaSneha DoriMedha WadhwaKhushali ShahBackground: Hospitalized children find difficulty in performing regular oral hygiene procedures. In such cases, direct application of herbal oils such as olive oil, Azadirachta indica (AI) (neem), and Curcuma zedoaria (CZ) (white turmeric) as antiplaque agents could be beneficial in maintaining oral hygiene. Aim: The aim of the study was to evaluate the efficacy of normal saline, extra virgin olive oil (EVOO), EVOO with 35% CZ, and EVOO with 30% AI on dental plaque and the count of Streptococcus mutans, Lactobacillus, and Candida albicans in hospitalized children. Settings and Design: This was a randomized control trial. Materials and Methods: 84 hospitalized children of age group 3–14 years were randomly divided by computer-generated random allocation into Group A-EVOO, Group B-EVOO + 35% CZ, Group C-EVOO + 30% AI, and Group D-normal saline with 21 participants in each group and applied with sterile gauze. The plaque score was recorded and analyzed by Loe and Silness plaque index. In addition, plaque sample for microbial analysis was collected from buccal/lingual surfaces, and CFU count was measured at baseline, 24 h, 48 h, and 72 h. Results: The four groups showed a reduction in plaque score and CFU counts from baseline to 72 h with P < 0.05 indicating a statistically significant difference. Group C has shown significant antimicrobial activity against Group A, Group B, and Group D (P = 0.0001) at 72 h. Conclusion: EVOO + 35% CZ showed the best treatment outcome in the reduction of microbial count followed by EVOO + 30% AI and EVOO. All the preparations including normal saline have antiplaque properties with the best outcome achieved in EVOO + 35% CZ and EVOO + 30% AI preparations.https://journals.lww.com/10.4103/jisppd.jisppd_68_25azadirachtacandida albicanscurcumadental plaquehospitalized childolive oilstreptococcus mutans
spellingShingle Anshula Deshpande
Simron Baishya
Sneha Dori
Medha Wadhwa
Khushali Shah
Clinical and microbiological evaluation of dental plaque on topical application of olive oil, olive oil with 35% Curcuma zedoaria, and olive oil with 30% Azadirachta indica in hospitalized children: A randomized control trial
Journal of Indian Society of Pedodontics and Preventive Dentistry
azadirachta
candida albicans
curcuma
dental plaque
hospitalized child
olive oil
streptococcus mutans
title Clinical and microbiological evaluation of dental plaque on topical application of olive oil, olive oil with 35% Curcuma zedoaria, and olive oil with 30% Azadirachta indica in hospitalized children: A randomized control trial
title_full Clinical and microbiological evaluation of dental plaque on topical application of olive oil, olive oil with 35% Curcuma zedoaria, and olive oil with 30% Azadirachta indica in hospitalized children: A randomized control trial
title_fullStr Clinical and microbiological evaluation of dental plaque on topical application of olive oil, olive oil with 35% Curcuma zedoaria, and olive oil with 30% Azadirachta indica in hospitalized children: A randomized control trial
title_full_unstemmed Clinical and microbiological evaluation of dental plaque on topical application of olive oil, olive oil with 35% Curcuma zedoaria, and olive oil with 30% Azadirachta indica in hospitalized children: A randomized control trial
title_short Clinical and microbiological evaluation of dental plaque on topical application of olive oil, olive oil with 35% Curcuma zedoaria, and olive oil with 30% Azadirachta indica in hospitalized children: A randomized control trial
title_sort clinical and microbiological evaluation of dental plaque on topical application of olive oil olive oil with 35 curcuma zedoaria and olive oil with 30 azadirachta indica in hospitalized children a randomized control trial
topic azadirachta
candida albicans
curcuma
dental plaque
hospitalized child
olive oil
streptococcus mutans
url https://journals.lww.com/10.4103/jisppd.jisppd_68_25
work_keys_str_mv AT anshuladeshpande clinicalandmicrobiologicalevaluationofdentalplaqueontopicalapplicationofoliveoiloliveoilwith35curcumazedoariaandoliveoilwith30azadirachtaindicainhospitalizedchildrenarandomizedcontroltrial
AT simronbaishya clinicalandmicrobiologicalevaluationofdentalplaqueontopicalapplicationofoliveoiloliveoilwith35curcumazedoariaandoliveoilwith30azadirachtaindicainhospitalizedchildrenarandomizedcontroltrial
AT snehadori clinicalandmicrobiologicalevaluationofdentalplaqueontopicalapplicationofoliveoiloliveoilwith35curcumazedoariaandoliveoilwith30azadirachtaindicainhospitalizedchildrenarandomizedcontroltrial
AT medhawadhwa clinicalandmicrobiologicalevaluationofdentalplaqueontopicalapplicationofoliveoiloliveoilwith35curcumazedoariaandoliveoilwith30azadirachtaindicainhospitalizedchildrenarandomizedcontroltrial
AT khushalishah clinicalandmicrobiologicalevaluationofdentalplaqueontopicalapplicationofoliveoiloliveoilwith35curcumazedoariaandoliveoilwith30azadirachtaindicainhospitalizedchildrenarandomizedcontroltrial