Reverse Correlation Uncovers More Complete Tinnitus Spectra
<italic>Goal:</italic> This study validates an approach to characterizing the sounds experienced by tinnitus patients via reverse correlation, with potential for characterizing a wider range of sounds than currently possible. <italic>Methods:</italic> Ten normal-hearing subje...
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| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
IEEE
2023-01-01
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| Series: | IEEE Open Journal of Engineering in Medicine and Biology |
| Subjects: | |
| Online Access: | https://ieeexplore.ieee.org/document/10129035/ |
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| Summary: | <italic>Goal:</italic> This study validates an approach to characterizing the sounds experienced by tinnitus patients via reverse correlation, with potential for characterizing a wider range of sounds than currently possible. <italic>Methods:</italic> Ten normal-hearing subjects assessed the subjective similarity of random auditory stimuli and target tinnitus-like sounds (“buzzing” and “roaring”). Reconstructions of the targets were obtained by regressing subject responses on the stimuli, and were compared for accuracy to the frequency spectra of the targets using Pearson's <inline-formula><tex-math notation="LaTeX">$r$</tex-math></inline-formula>. <italic>Results:</italic> Reconstruction accuracy was significantly higher than chance across subjects: buzzing: <inline-formula><tex-math notation="LaTeX">$0.52 \pm 0.27$</tex-math></inline-formula> (mean <inline-formula><tex-math notation="LaTeX">$\pm$</tex-math></inline-formula> s.d.), <inline-formula><tex-math notation="LaTeX">$t(9) = 5.766$</tex-math></inline-formula>, <inline-formula><tex-math notation="LaTeX">$p < 0.001$</tex-math></inline-formula>; roaring: <inline-formula><tex-math notation="LaTeX">$0.62 \pm 0.23$</tex-math></inline-formula>, <inline-formula><tex-math notation="LaTeX">$t(9) = 5.76$</tex-math></inline-formula>, <inline-formula><tex-math notation="LaTeX">$p < 0.001$</tex-math></inline-formula>; combined: <inline-formula><tex-math notation="LaTeX">$0.57 \pm 0.25$</tex-math></inline-formula>, <inline-formula><tex-math notation="LaTeX">$t(19) = 7.542$</tex-math></inline-formula>, <inline-formula><tex-math notation="LaTeX">$p < 0.001$</tex-math></inline-formula>. <italic>Conclusion:</italic> Reverse correlation can accurately reconstruct non-tonal tinnitus-like sounds in normal-hearing subjects, indicating its potential for characterizing the sounds experienced by patients with non-tonal tinnitus. |
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| ISSN: | 2644-1276 |