Rb substantially compensates for the double loss of p130 and p107 in adult but not embryonic neural stem cell lineages
Abstract The Retinoblastoma (Rb) family of pocket proteins (p107, Rb, and p130) controls all aspects of neurogenesis from stem cell activation to long-term neuronal survival in the brain. Previous studies have reported non-overlapping, often complementary, roles for these cell cycle regulators with...
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| Main Authors: | Reem Swaidan, Ahmad Daher, Anthony T. Bejjani, Yara E. El Atie, Yasmina Chehab, Razan Bou Hamdan, Renaud Vandenbosch, Ruth S. Slack, Saad Omais, Noël Ghanem |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Publishing Group
2025-07-01
|
| Series: | Cell Death and Disease |
| Online Access: | https://doi.org/10.1038/s41419-025-07815-6 |
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