Sensitive Electrochemical Determination of Vanillin Using a Bimetallic Hydroxide and Reduced Graphene Oxide Nanocomposite

Vanillin (VAN) is an organic compound which not only functions as a flavoring and fragrance enhancer in some foods but also has antioxidant, anti-inflammatory, anti-cancer, and anti-depressant effects. However, the excessive use of VAN can be associated with negative side effects on human health. As...

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Bibliographic Details
Main Authors: Shamim Ahmed Hira, Jonathan Quintal, Aicheng Chen
Format: Article
Language:English
Published: MDPI AG 2025-03-01
Series:Sensors
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Online Access:https://www.mdpi.com/1424-8220/25/6/1694
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Summary:Vanillin (VAN) is an organic compound which not only functions as a flavoring and fragrance enhancer in some foods but also has antioxidant, anti-inflammatory, anti-cancer, and anti-depressant effects. However, the excessive use of VAN can be associated with negative side effects on human health. As a result, it is crucial to find a reliable method for the rapid determination of VAN to enhance food safety. Herein, we developed a sensor using Ni and Co bimetallic hydroxide and reduced graphene oxide nanostructure (NiCo(OH)<sub>2</sub>.rGO). Our prepared material was characterized using various physico-chemical techniques. The electrocatalytic efficiency of the NiCo(OH)<sub>2</sub>.rGO-modified glassy carbon electrode was investigated using cyclic and square wave voltammetry. The developed sensor showed a limit of detection of 6.1 nM and a linear range of 5–140 nM. The synergistic effect of NiCo(OH)<sub>2</sub> and rGO improved the active sites and enhanced its catalytic efficiency. The practical applicability of the prepared sensor was investigated for the determination of VAN in food samples such as biscuits and chocolates, showing promise in practical applications.
ISSN:1424-8220