Evaluation of the α<sub>2</sub>-adrenergic Agonist Mafedine Effects on White Outbred Mouse Behaviour Following Acute Administration

Evaluation of the α<sub>2</sub>-adrenergic Agonist Mafedine Effects on White Outbred Mouse Behaviour Following Acute Administration

Introduction. α2-adrenergic agonists are not only used as antihypertensive and sedative agents, but are also of interest as potential medications for the treatment of neurological disorders. Previous research has shown a compound from this class, 6-oxo-1-phenyl-2-(phenylamino)-1,6-dihydropyrimidine-...

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Bibliographic Details
Main Authors: N. S. Kurmazov, S. A. Chervonetskiy, V. A. Prikhodko, Yu. I. Sysoev, S. V. Okovityi
Format: Article
Language:Russian
Published: LLC Center of Pharmaceutical Analytics (LLC «CPHA») 2023-12-01
Series:Разработка и регистрация лекарственных средств
Subjects:
α<sub>2</sub>-adrenergic agonists
mafedine
mice
behavioural testing
open field
elevated plus maze
light/dark box
Online Access:https://www.pharmjournal.ru/jour/article/view/1662
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