Graphene: A Versatile Carbon-Based Material for Bone Tissue Engineering
The development of materials and strategies that can influence stem cell attachment, proliferation, and differentiation towards osteoblasts is of high interest to promote faster healing and reconstructions of large bone defects. Graphene and its derivatives (graphene oxide and reduced graphene oxide...
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| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2015-01-01
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| Series: | Stem Cells International |
| Online Access: | http://dx.doi.org/10.1155/2015/804213 |
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| _version_ | 1850168324481089536 |
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| author | Nileshkumar Dubey Ricardo Bentini Intekhab Islam Tong Cao Antonio Helio Castro Neto Vinicius Rosa |
| author_facet | Nileshkumar Dubey Ricardo Bentini Intekhab Islam Tong Cao Antonio Helio Castro Neto Vinicius Rosa |
| author_sort | Nileshkumar Dubey |
| collection | DOAJ |
| description | The development of materials and strategies that can influence stem cell attachment, proliferation, and differentiation towards osteoblasts is of high interest to promote faster healing and reconstructions of large bone defects. Graphene and its derivatives (graphene oxide and reduced graphene oxide) have received increasing attention for biomedical applications as they present remarkable properties such as high surface area, high mechanical strength, and ease of functionalization. These biocompatible carbon-based materials can induce and sustain stem cell growth and differentiation into various lineages. Furthermore, graphene has the ability to promote and enhance osteogenic differentiation making it an interesting material for bone regeneration research. This paper will review the important advances in the ability of graphene and its related forms to induce stem cells differentiation into osteogenic lineages. |
| format | Article |
| id | doaj-art-d85b1cad050f4c82af8aaec8a8ebeedb |
| institution | OA Journals |
| issn | 1687-966X 1687-9678 |
| language | English |
| publishDate | 2015-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Stem Cells International |
| spelling | doaj-art-d85b1cad050f4c82af8aaec8a8ebeedb2025-08-20T02:20:58ZengWileyStem Cells International1687-966X1687-96782015-01-01201510.1155/2015/804213804213Graphene: A Versatile Carbon-Based Material for Bone Tissue EngineeringNileshkumar Dubey0Ricardo Bentini1Intekhab Islam2Tong Cao3Antonio Helio Castro Neto4Vinicius Rosa5Discipline of Oral Sciences, Faculty of Dentistry, National University of Singapore, 119083, SingaporeCentre for Advanced 2D Materials and Graphene Research Centre, National University of Singapore, 117542, SingaporeDiscipline of Oral and Maxillofacial Surgery, Faculty of Dentistry, National University of Singapore, 119083, SingaporeDiscipline of Oral Sciences, Faculty of Dentistry, National University of Singapore, 119083, SingaporeCentre for Advanced 2D Materials and Graphene Research Centre, National University of Singapore, 117542, SingaporeDiscipline of Oral Sciences, Faculty of Dentistry, National University of Singapore, 119083, SingaporeThe development of materials and strategies that can influence stem cell attachment, proliferation, and differentiation towards osteoblasts is of high interest to promote faster healing and reconstructions of large bone defects. Graphene and its derivatives (graphene oxide and reduced graphene oxide) have received increasing attention for biomedical applications as they present remarkable properties such as high surface area, high mechanical strength, and ease of functionalization. These biocompatible carbon-based materials can induce and sustain stem cell growth and differentiation into various lineages. Furthermore, graphene has the ability to promote and enhance osteogenic differentiation making it an interesting material for bone regeneration research. This paper will review the important advances in the ability of graphene and its related forms to induce stem cells differentiation into osteogenic lineages.http://dx.doi.org/10.1155/2015/804213 |
| spellingShingle | Nileshkumar Dubey Ricardo Bentini Intekhab Islam Tong Cao Antonio Helio Castro Neto Vinicius Rosa Graphene: A Versatile Carbon-Based Material for Bone Tissue Engineering Stem Cells International |
| title | Graphene: A Versatile Carbon-Based Material for Bone Tissue Engineering |
| title_full | Graphene: A Versatile Carbon-Based Material for Bone Tissue Engineering |
| title_fullStr | Graphene: A Versatile Carbon-Based Material for Bone Tissue Engineering |
| title_full_unstemmed | Graphene: A Versatile Carbon-Based Material for Bone Tissue Engineering |
| title_short | Graphene: A Versatile Carbon-Based Material for Bone Tissue Engineering |
| title_sort | graphene a versatile carbon based material for bone tissue engineering |
| url | http://dx.doi.org/10.1155/2015/804213 |
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