Reassessing the Role for Lamivudine in Chronic Hepatitis B Infection: A Four-Year Cohort Analysis

The data supporting the use of antiviral agents other than lamivudine in the management of patients with hepatitis B virus (HBV) infection are based on highly selected clinical trial populations that may not be representative of typical HBV-infected populations encountered in many clinics. Despite i...

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Main Authors: Tahir Shaikh, Curtis Cooper
Format: Article
Language:English
Published: Wiley 2012-01-01
Series:Canadian Journal of Gastroenterology
Online Access:http://dx.doi.org/10.1155/2012/936259
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author Tahir Shaikh
Curtis Cooper
author_facet Tahir Shaikh
Curtis Cooper
author_sort Tahir Shaikh
collection DOAJ
description The data supporting the use of antiviral agents other than lamivudine in the management of patients with hepatitis B virus (HBV) infection are based on highly selected clinical trial populations that may not be representative of typical HBV-infected populations encountered in many clinics. Despite its limitations, however, lamivudine is relatively inexpensive and widely available and, in carefully selected patients, can still be successfully used to achieve long-term HBV suppression. This study investigated the long-term effectiveness of lamivudine in an adherent, frequently monitored, noninvestigational HBV-infected cohort.
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spelling doaj-art-d84c993971b54dcd8bb3fe370b8c45762025-02-03T01:21:55ZengWileyCanadian Journal of Gastroenterology0835-79002012-01-0126314815010.1155/2012/936259Reassessing the Role for Lamivudine in Chronic Hepatitis B Infection: A Four-Year Cohort AnalysisTahir Shaikh0Curtis Cooper1Department of Medicine, University of Ottawa, CanadaDepartment of Medicine, University of Ottawa, CanadaThe data supporting the use of antiviral agents other than lamivudine in the management of patients with hepatitis B virus (HBV) infection are based on highly selected clinical trial populations that may not be representative of typical HBV-infected populations encountered in many clinics. Despite its limitations, however, lamivudine is relatively inexpensive and widely available and, in carefully selected patients, can still be successfully used to achieve long-term HBV suppression. This study investigated the long-term effectiveness of lamivudine in an adherent, frequently monitored, noninvestigational HBV-infected cohort.http://dx.doi.org/10.1155/2012/936259
spellingShingle Tahir Shaikh
Curtis Cooper
Reassessing the Role for Lamivudine in Chronic Hepatitis B Infection: A Four-Year Cohort Analysis
Canadian Journal of Gastroenterology
title Reassessing the Role for Lamivudine in Chronic Hepatitis B Infection: A Four-Year Cohort Analysis
title_full Reassessing the Role for Lamivudine in Chronic Hepatitis B Infection: A Four-Year Cohort Analysis
title_fullStr Reassessing the Role for Lamivudine in Chronic Hepatitis B Infection: A Four-Year Cohort Analysis
title_full_unstemmed Reassessing the Role for Lamivudine in Chronic Hepatitis B Infection: A Four-Year Cohort Analysis
title_short Reassessing the Role for Lamivudine in Chronic Hepatitis B Infection: A Four-Year Cohort Analysis
title_sort reassessing the role for lamivudine in chronic hepatitis b infection a four year cohort analysis
url http://dx.doi.org/10.1155/2012/936259
work_keys_str_mv AT tahirshaikh reassessingtheroleforlamivudineinchronichepatitisbinfectionafouryearcohortanalysis
AT curtiscooper reassessingtheroleforlamivudineinchronichepatitisbinfectionafouryearcohortanalysis