Individual differences in the amount and timing of salivary melatonin secretion.
The aim of this study was to examine individual differences in a large sample of complete melatonin profiles not suppressed by light and search for possible associations between the amount and timing of melatonin secretion and a multitude of lifestyle variables. The melatonin profiles were derived f...
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Public Library of Science (PLoS)
2008-08-01
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| Series: | PLoS ONE |
| Online Access: | https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0003055&type=printable |
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| author | Helen J Burgess Louis F Fogg |
| author_facet | Helen J Burgess Louis F Fogg |
| author_sort | Helen J Burgess |
| collection | DOAJ |
| description | The aim of this study was to examine individual differences in a large sample of complete melatonin profiles not suppressed by light and search for possible associations between the amount and timing of melatonin secretion and a multitude of lifestyle variables. The melatonin profiles were derived from saliva samples collected every 30 minutes in dim light from 85 healthy women and 85 healthy men aged 18-45 years. There was a large individual variability in the amount of melatonin secreted with peak values ranging from 2 to 84 pg/ml. The onset of melatonin secretion ranged from 18:13 to 00:26 hours. The use of hormonal birth control, reduced levels of employment, a smaller number of days on a fixed sleep schedule, increased day length and lower weight were associated with an increased amplitude of melatonin secretion. The use of hormonal birth control, contact lenses, a younger age, and lower ratings of mania and paranoia were associated with a longer duration of melatonin secretion. An earlier occurrence of the onset of melatonin secretion was associated with an earlier wake time, more morningness and the absence of a bed partner. Lifestyle and behavioral variables were only able to explain about 15% of the individual variability in the amount of melatonin secretion, which is likely because of a substantial genetic influence on the levels of melatonin secretion. |
| format | Article |
| id | doaj-art-d844af2fbdc04596b6d8b8e869d82bfb |
| institution | Kabale University |
| issn | 1932-6203 |
| language | English |
| publishDate | 2008-08-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLoS ONE |
| spelling | doaj-art-d844af2fbdc04596b6d8b8e869d82bfb2025-08-20T03:46:19ZengPublic Library of Science (PLoS)PLoS ONE1932-62032008-08-0138e305510.1371/journal.pone.0003055Individual differences in the amount and timing of salivary melatonin secretion.Helen J BurgessLouis F FoggThe aim of this study was to examine individual differences in a large sample of complete melatonin profiles not suppressed by light and search for possible associations between the amount and timing of melatonin secretion and a multitude of lifestyle variables. The melatonin profiles were derived from saliva samples collected every 30 minutes in dim light from 85 healthy women and 85 healthy men aged 18-45 years. There was a large individual variability in the amount of melatonin secreted with peak values ranging from 2 to 84 pg/ml. The onset of melatonin secretion ranged from 18:13 to 00:26 hours. The use of hormonal birth control, reduced levels of employment, a smaller number of days on a fixed sleep schedule, increased day length and lower weight were associated with an increased amplitude of melatonin secretion. The use of hormonal birth control, contact lenses, a younger age, and lower ratings of mania and paranoia were associated with a longer duration of melatonin secretion. An earlier occurrence of the onset of melatonin secretion was associated with an earlier wake time, more morningness and the absence of a bed partner. Lifestyle and behavioral variables were only able to explain about 15% of the individual variability in the amount of melatonin secretion, which is likely because of a substantial genetic influence on the levels of melatonin secretion.https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0003055&type=printable |
| spellingShingle | Helen J Burgess Louis F Fogg Individual differences in the amount and timing of salivary melatonin secretion. PLoS ONE |
| title | Individual differences in the amount and timing of salivary melatonin secretion. |
| title_full | Individual differences in the amount and timing of salivary melatonin secretion. |
| title_fullStr | Individual differences in the amount and timing of salivary melatonin secretion. |
| title_full_unstemmed | Individual differences in the amount and timing of salivary melatonin secretion. |
| title_short | Individual differences in the amount and timing of salivary melatonin secretion. |
| title_sort | individual differences in the amount and timing of salivary melatonin secretion |
| url | https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0003055&type=printable |
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