A feasibility study for a new one-day protocol for [99mTc]TcDTPA2- and [99mTc]TcDMSA2- renal scintigraphy on dilated and non-dilated pediatric patients: underlying rationale

Purpose. This work aimed at evaluating the possibility of performing renal exams of dynamic renal (DRS) and static renal (SRS) scintigraphy on the same day (one-day protocol, ODP), exams that are currently performed in two days. Approach. 25 infants (50 kidneys) of both genders, aged 8.4 ± 5.9 years...

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Main Authors: Fabiana Trevisan, Beatriz Nascimento, Gabriel Chibana, Luciana Maeda, Marta Vila, Valquiria Yoshida, Norberto Aranha, Victor M. Balcão, José Martins Oliveira Júnior
Format: Article
Language:English
Published: Brazilian Radiation Protection Society (Sociedade Brasileira de Proteção Radiológica, SBPR) 2023-03-01
Series:Brazilian Journal of Radiation Sciences
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Online Access:https://bjrs.org.br/revista/index.php/REVISTA/article/view/2158
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author Fabiana Trevisan
Beatriz Nascimento
Gabriel Chibana
Luciana Maeda
Marta Vila
Valquiria Yoshida
Norberto Aranha
Victor M. Balcão
José Martins Oliveira Júnior
author_facet Fabiana Trevisan
Beatriz Nascimento
Gabriel Chibana
Luciana Maeda
Marta Vila
Valquiria Yoshida
Norberto Aranha
Victor M. Balcão
José Martins Oliveira Júnior
author_sort Fabiana Trevisan
collection DOAJ
description Purpose. This work aimed at evaluating the possibility of performing renal exams of dynamic renal (DRS) and static renal (SRS) scintigraphy on the same day (one-day protocol, ODP), exams that are currently performed in two days. Approach. 25 infants (50 kidneys) of both genders, aged 8.4 ± 5.9 years, underwent an F+20 DRS protocol with [99mTc]TcDTPA2- followed by [99mTc]TcDMSA2- administration for the performance of SRS images at 3, 6 and 24 h. Dynamic images (DRS) were classified as dilated (D), undetermined (U), and non-dilated (P). Static images (SRS) were classified as: depressed in accented degree (DA); depressed in moderate degree (DM); depressed in mild degree (DL) and normal (NL). Results. Out of the 25 patients (50 kidneys), 7 (14 kidneys) were excluded by functional exclusion, hence 18 patients (36 kidneys) were clinically compared regarding their static images after 3, 6 and 24 h, resulting in 33.0% of dilated and 66.7% non-dilated. Only two patients of the dilated group were classified as obstructed. At the group with non-dilated and dilated but non-obstructed kidneys, 100% of them had the same clinical classification at 6 and 24 h images. Conclusions. Performance of both DRS and SRS exams in a single day for pediatric patients, when medical requests are carried out jointly, is feasible in a population with or without dilatation, when the difference between dynamic and static images is of at least 6 h. Due to the small number of obstructed kidneys in this study, further evaluation in this population is needed.
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spelling doaj-art-d82e99da5c5d4061b21699540087c8a52025-08-20T03:27:52ZengBrazilian Radiation Protection Society (Sociedade Brasileira de Proteção Radiológica, SBPR)Brazilian Journal of Radiation Sciences2319-06122023-03-01110110.15392/2319-0612.2023.21581776A feasibility study for a new one-day protocol for [99mTc]TcDTPA2- and [99mTc]TcDMSA2- renal scintigraphy on dilated and non-dilated pediatric patients: underlying rationaleFabiana Trevisan0Beatriz Nascimento1Gabriel Chibana2Luciana Maeda3Marta Vila4Valquiria Yoshida5Norberto Aranha6Victor M. Balcão7José Martins Oliveira Júnior8University of SorocabaIDS - Institute of Diagnosis of SorocabaHospital Santa MarcelinaHospital Santa MarcelinaUniversity of SorocabaUniversity of SorocabaUniversity of SorocabaUniversity of SorocabaPhageLab - Laboratory of Biofilms and BacteriophagesCidade Universitária Prof. Aldo VannucchiRodovia Raposo Tavares, km 92.5CEP 18023-000 Sorocaba/SPBrazilUniversity of SorocabaPurpose. This work aimed at evaluating the possibility of performing renal exams of dynamic renal (DRS) and static renal (SRS) scintigraphy on the same day (one-day protocol, ODP), exams that are currently performed in two days. Approach. 25 infants (50 kidneys) of both genders, aged 8.4 ± 5.9 years, underwent an F+20 DRS protocol with [99mTc]TcDTPA2- followed by [99mTc]TcDMSA2- administration for the performance of SRS images at 3, 6 and 24 h. Dynamic images (DRS) were classified as dilated (D), undetermined (U), and non-dilated (P). Static images (SRS) were classified as: depressed in accented degree (DA); depressed in moderate degree (DM); depressed in mild degree (DL) and normal (NL). Results. Out of the 25 patients (50 kidneys), 7 (14 kidneys) were excluded by functional exclusion, hence 18 patients (36 kidneys) were clinically compared regarding their static images after 3, 6 and 24 h, resulting in 33.0% of dilated and 66.7% non-dilated. Only two patients of the dilated group were classified as obstructed. At the group with non-dilated and dilated but non-obstructed kidneys, 100% of them had the same clinical classification at 6 and 24 h images. Conclusions. Performance of both DRS and SRS exams in a single day for pediatric patients, when medical requests are carried out jointly, is feasible in a population with or without dilatation, when the difference between dynamic and static images is of at least 6 h. Due to the small number of obstructed kidneys in this study, further evaluation in this population is needed.https://bjrs.org.br/revista/index.php/REVISTA/article/view/2158radionuclide imagingpediatric nephrologyrenal cortical scintigraphy
spellingShingle Fabiana Trevisan
Beatriz Nascimento
Gabriel Chibana
Luciana Maeda
Marta Vila
Valquiria Yoshida
Norberto Aranha
Victor M. Balcão
José Martins Oliveira Júnior
A feasibility study for a new one-day protocol for [99mTc]TcDTPA2- and [99mTc]TcDMSA2- renal scintigraphy on dilated and non-dilated pediatric patients: underlying rationale
Brazilian Journal of Radiation Sciences
radionuclide imaging
pediatric nephrology
renal cortical scintigraphy
title A feasibility study for a new one-day protocol for [99mTc]TcDTPA2- and [99mTc]TcDMSA2- renal scintigraphy on dilated and non-dilated pediatric patients: underlying rationale
title_full A feasibility study for a new one-day protocol for [99mTc]TcDTPA2- and [99mTc]TcDMSA2- renal scintigraphy on dilated and non-dilated pediatric patients: underlying rationale
title_fullStr A feasibility study for a new one-day protocol for [99mTc]TcDTPA2- and [99mTc]TcDMSA2- renal scintigraphy on dilated and non-dilated pediatric patients: underlying rationale
title_full_unstemmed A feasibility study for a new one-day protocol for [99mTc]TcDTPA2- and [99mTc]TcDMSA2- renal scintigraphy on dilated and non-dilated pediatric patients: underlying rationale
title_short A feasibility study for a new one-day protocol for [99mTc]TcDTPA2- and [99mTc]TcDMSA2- renal scintigraphy on dilated and non-dilated pediatric patients: underlying rationale
title_sort feasibility study for a new one day protocol for 99mtc tcdtpa2 and 99mtc tcdmsa2 renal scintigraphy on dilated and non dilated pediatric patients underlying rationale
topic radionuclide imaging
pediatric nephrology
renal cortical scintigraphy
url https://bjrs.org.br/revista/index.php/REVISTA/article/view/2158
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