Cat Scratch Disease: A Diagnostic Challenge in Cervical Lymphadenopathy

Introduction: Cat scratch disease typically manifests as long standing regional lymphadenopathy, though clinical features may cover a wide spectrum. Lack of definite history of cat scratch, atypical presentation, non-availability of serological tests and misleading needle cytology may often lead to...

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Main Authors: Bipin Kishore Prasad, Yamuna Ranganathan, Gunjan Dwivedi, Devika Gupta
Format: Article
Language:English
Published: The Association of Otolaryngologists of India, West Bengal 2024-05-01
Series:Bengal Journal of Otolaryngology and Head Neck Surgery
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Online Access:https://bjohns.in/journal23/index.php/bjohns/article/view/84
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author Bipin Kishore Prasad
Yamuna Ranganathan
Gunjan Dwivedi
Devika Gupta
author_facet Bipin Kishore Prasad
Yamuna Ranganathan
Gunjan Dwivedi
Devika Gupta
author_sort Bipin Kishore Prasad
collection DOAJ
description Introduction: Cat scratch disease typically manifests as long standing regional lymphadenopathy, though clinical features may cover a wide spectrum. Lack of definite history of cat scratch, atypical presentation, non-availability of serological tests and misleading needle cytology may often lead to delay in diagnosis. Case report: A 44 years old diabetic female, presented with persistent fever for 15 days followed by 4x4cm, tender tense swelling in left parotid region extending into upper neck. Her blood sugar was deranged. Polymorphonuclear leucocytosis was noted. Radiological investigation showed lymph nodal conglomeration involving level II, III and IV with non-enhancing necrotic areas within it. Mass was abutting Internal Jugular Vein, which was attenuated cranially. Aggressive antibiotics treatment and optimal glycemic control failed to resolve fever and lymphadenopathy, hence excision of neck mass was done which was reported histopathologically as Cat Scratch Disease. Conclusion: While ruling out tuberculosis, Epstein Barr-Virus infection, acute bacterial lymphadenitis or malignant disease, Cat Scratch Disease should be included in the differential diagnosis of lymphadenopathies in head-neck region so that possibility of antibiotic abuse, an unnecessary biopsy, long term antitubercular drug therapy or even surgical treatment may be avoided. Keywords: Cat Scratch Disease; Bartonella henselae; lymphadenopathy; serological test
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institution Kabale University
issn 2395-2393
2395-2407
language English
publishDate 2024-05-01
publisher The Association of Otolaryngologists of India, West Bengal
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series Bengal Journal of Otolaryngology and Head Neck Surgery
spelling doaj-art-d82e8a23bdbd424aae9f7ff972b98ee32025-02-11T09:43:33ZengThe Association of Otolaryngologists of India, West BengalBengal Journal of Otolaryngology and Head Neck Surgery2395-23932395-24072024-05-0131310.47210/bjohns.2023.v31i3.84Cat Scratch Disease: A Diagnostic Challenge in Cervical LymphadenopathyBipin Kishore Prasad0Yamuna Ranganathan1Gunjan Dwivedi2Devika Gupta3Command Hospital (Central Command), LucknowCommand hospital (Eastern Command), Kolkata-700027Command Hospital (Eastern Command), KolkataCommand hospital (Eastern Command), Kolkata Introduction: Cat scratch disease typically manifests as long standing regional lymphadenopathy, though clinical features may cover a wide spectrum. Lack of definite history of cat scratch, atypical presentation, non-availability of serological tests and misleading needle cytology may often lead to delay in diagnosis. Case report: A 44 years old diabetic female, presented with persistent fever for 15 days followed by 4x4cm, tender tense swelling in left parotid region extending into upper neck. Her blood sugar was deranged. Polymorphonuclear leucocytosis was noted. Radiological investigation showed lymph nodal conglomeration involving level II, III and IV with non-enhancing necrotic areas within it. Mass was abutting Internal Jugular Vein, which was attenuated cranially. Aggressive antibiotics treatment and optimal glycemic control failed to resolve fever and lymphadenopathy, hence excision of neck mass was done which was reported histopathologically as Cat Scratch Disease. Conclusion: While ruling out tuberculosis, Epstein Barr-Virus infection, acute bacterial lymphadenitis or malignant disease, Cat Scratch Disease should be included in the differential diagnosis of lymphadenopathies in head-neck region so that possibility of antibiotic abuse, an unnecessary biopsy, long term antitubercular drug therapy or even surgical treatment may be avoided. Keywords: Cat Scratch Disease; Bartonella henselae; lymphadenopathy; serological test https://bjohns.in/journal23/index.php/bjohns/article/view/84Cat Scratch DiseaseBartonella henselaelymphadenopathyserological test
spellingShingle Bipin Kishore Prasad
Yamuna Ranganathan
Gunjan Dwivedi
Devika Gupta
Cat Scratch Disease: A Diagnostic Challenge in Cervical Lymphadenopathy
Bengal Journal of Otolaryngology and Head Neck Surgery
Cat Scratch Disease
Bartonella henselae
lymphadenopathy
serological test
title Cat Scratch Disease: A Diagnostic Challenge in Cervical Lymphadenopathy
title_full Cat Scratch Disease: A Diagnostic Challenge in Cervical Lymphadenopathy
title_fullStr Cat Scratch Disease: A Diagnostic Challenge in Cervical Lymphadenopathy
title_full_unstemmed Cat Scratch Disease: A Diagnostic Challenge in Cervical Lymphadenopathy
title_short Cat Scratch Disease: A Diagnostic Challenge in Cervical Lymphadenopathy
title_sort cat scratch disease a diagnostic challenge in cervical lymphadenopathy
topic Cat Scratch Disease
Bartonella henselae
lymphadenopathy
serological test
url https://bjohns.in/journal23/index.php/bjohns/article/view/84
work_keys_str_mv AT bipinkishoreprasad catscratchdiseaseadiagnosticchallengeincervicallymphadenopathy
AT yamunaranganathan catscratchdiseaseadiagnosticchallengeincervicallymphadenopathy
AT gunjandwivedi catscratchdiseaseadiagnosticchallengeincervicallymphadenopathy
AT devikagupta catscratchdiseaseadiagnosticchallengeincervicallymphadenopathy