In-hospital cardiac arrest in middle-income settings: A comprehensive analysis of clinical profiles and outcomes of both adults and pediatrics
Background: In hospital cardiac arrest is associated with poor survival despite basic and advanced life support measures. This study aimed to identify the clinical characteristics and outcomes of cardiac arrests occurring during in-hospital admission to the tertiary care center in Pakistan. Method:...
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| Format: | Article |
| Language: | English |
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Elsevier
2024-12-01
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| Series: | Resuscitation Plus |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2666520424002261 |
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| author | Muhammad Faisal Khan Omer Shafiq Sana Hirani Amber Sabeen Sijal Akhtar Sheikh Qalab Abbas Tahir Munir Huba Atiq Yasmin Hashwani Asad Latif |
| author_facet | Muhammad Faisal Khan Omer Shafiq Sana Hirani Amber Sabeen Sijal Akhtar Sheikh Qalab Abbas Tahir Munir Huba Atiq Yasmin Hashwani Asad Latif |
| author_sort | Muhammad Faisal Khan |
| collection | DOAJ |
| description | Background: In hospital cardiac arrest is associated with poor survival despite basic and advanced life support measures. This study aimed to identify the clinical characteristics and outcomes of cardiac arrests occurring during in-hospital admission to the tertiary care center in Pakistan. Method: A retrospective, cross-sectional study at Aga Khan University Hospital from 2021 to 2023 analyzed 230 cardiac arrest cases. Data included demographics, arrest type, timing, initial rhythm, resuscitation duration, and arrest location. American Heart Association guidelines were adhered to for life support. The main outcomes focused on the return of spontaneous circulation survival to hospital discharge. Results: During the study, 230 cardiac arrests were observed: 152 in adults (mean age 57.8, 142 shockable cases, ROSC 52.6 %, alive at discharge 28.3 %) and 78 in pediatric patients (mean age 4.99, non-shockable rhythm 85.9 %, ROSC 51.3 %, alive at discharge 17.9 %). Adult Charles comorbidity index: 2.88 (SD±2.08), pediatric index: 0.610 (SD±0.88). Survival rates were lower with a high comorbidity index and code duration > 20 min. Conclusion: The study provides valuable observational data that challenges global survival rates for in-hospital cardiac arrest. It highlights how factors like being in monitored units and the presence of rapid response teams can lead to higher survival rates. The research underscores the influence of comorbidities, initial rhythms, and the duration of resuscitation efforts on patient outcomes, emphasizing the need for more research, especially in settings with limited resources. |
| format | Article |
| id | doaj-art-d829ce65fe0e45818fe0403eaa95d7b1 |
| institution | OA Journals |
| issn | 2666-5204 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Resuscitation Plus |
| spelling | doaj-art-d829ce65fe0e45818fe0403eaa95d7b12025-08-20T02:32:21ZengElsevierResuscitation Plus2666-52042024-12-012010077510.1016/j.resplu.2024.100775In-hospital cardiac arrest in middle-income settings: A comprehensive analysis of clinical profiles and outcomes of both adults and pediatricsMuhammad Faisal Khan0Omer Shafiq1Sana Hirani2Amber Sabeen3Sijal Akhtar Sheikh4Qalab Abbas5Tahir Munir6Huba Atiq7Yasmin Hashwani8Asad Latif9Department of Anesthesiology, Aga Khan University, Karachi, Pakistan; Corresponding author at: Aga Khan University, Stadium Road, Karachi P.O. Box 3500, Pakistan.Department of Anesthesiology, Aga Khan University, Karachi, PakistanDepartment of Nursing Services and Department of MedicineDepartment of Medicine, Aga Khan University, Karachi, PakistanCenter of Trauma and ExcellenceDepartment of Pediatrics and Child Health, Karachi, PakistanDepartment of Anesthesiology, Aga Khan University, Karachi, PakistanDepartment of Anesthesiology, Aga Khan University, Karachi, PakistanDepartment of Nursing Services and Department of MedicineDepartment of Anesthesiology, Aga Khan University, Karachi, PakistanBackground: In hospital cardiac arrest is associated with poor survival despite basic and advanced life support measures. This study aimed to identify the clinical characteristics and outcomes of cardiac arrests occurring during in-hospital admission to the tertiary care center in Pakistan. Method: A retrospective, cross-sectional study at Aga Khan University Hospital from 2021 to 2023 analyzed 230 cardiac arrest cases. Data included demographics, arrest type, timing, initial rhythm, resuscitation duration, and arrest location. American Heart Association guidelines were adhered to for life support. The main outcomes focused on the return of spontaneous circulation survival to hospital discharge. Results: During the study, 230 cardiac arrests were observed: 152 in adults (mean age 57.8, 142 shockable cases, ROSC 52.6 %, alive at discharge 28.3 %) and 78 in pediatric patients (mean age 4.99, non-shockable rhythm 85.9 %, ROSC 51.3 %, alive at discharge 17.9 %). Adult Charles comorbidity index: 2.88 (SD±2.08), pediatric index: 0.610 (SD±0.88). Survival rates were lower with a high comorbidity index and code duration > 20 min. Conclusion: The study provides valuable observational data that challenges global survival rates for in-hospital cardiac arrest. It highlights how factors like being in monitored units and the presence of rapid response teams can lead to higher survival rates. The research underscores the influence of comorbidities, initial rhythms, and the duration of resuscitation efforts on patient outcomes, emphasizing the need for more research, especially in settings with limited resources.http://www.sciencedirect.com/science/article/pii/S2666520424002261In-hospital cardiac arrestCardiopulmonary resuscitationEpidemiologyOutcome |
| spellingShingle | Muhammad Faisal Khan Omer Shafiq Sana Hirani Amber Sabeen Sijal Akhtar Sheikh Qalab Abbas Tahir Munir Huba Atiq Yasmin Hashwani Asad Latif In-hospital cardiac arrest in middle-income settings: A comprehensive analysis of clinical profiles and outcomes of both adults and pediatrics Resuscitation Plus In-hospital cardiac arrest Cardiopulmonary resuscitation Epidemiology Outcome |
| title | In-hospital cardiac arrest in middle-income settings: A comprehensive analysis of clinical profiles and outcomes of both adults and pediatrics |
| title_full | In-hospital cardiac arrest in middle-income settings: A comprehensive analysis of clinical profiles and outcomes of both adults and pediatrics |
| title_fullStr | In-hospital cardiac arrest in middle-income settings: A comprehensive analysis of clinical profiles and outcomes of both adults and pediatrics |
| title_full_unstemmed | In-hospital cardiac arrest in middle-income settings: A comprehensive analysis of clinical profiles and outcomes of both adults and pediatrics |
| title_short | In-hospital cardiac arrest in middle-income settings: A comprehensive analysis of clinical profiles and outcomes of both adults and pediatrics |
| title_sort | in hospital cardiac arrest in middle income settings a comprehensive analysis of clinical profiles and outcomes of both adults and pediatrics |
| topic | In-hospital cardiac arrest Cardiopulmonary resuscitation Epidemiology Outcome |
| url | http://www.sciencedirect.com/science/article/pii/S2666520424002261 |
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