Primary Zonal High Intensity Focused Ultrasound for Prostate Cancer: Results of a Prospective Phase IIa Feasibility Study

Aims. In this study we report our results with storage of cryopreserved semen intended for preservation and subsequent infertility treatment in men with testicular cancer during the last 18 years. Methods. Cryopreserved semen of 523 men with testicular cancer was collected between October 1995 and t...

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Main Authors: Roland Van Velthoven, Fouad Aoun, Ksenija Limani, Krishna Narahari, Marc Lemort, Alexandre Peltier
Format: Article
Language:English
Published: Wiley 2014-01-01
Series:Prostate Cancer
Online Access:http://dx.doi.org/10.1155/2014/756189
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author Roland Van Velthoven
Fouad Aoun
Ksenija Limani
Krishna Narahari
Marc Lemort
Alexandre Peltier
author_facet Roland Van Velthoven
Fouad Aoun
Ksenija Limani
Krishna Narahari
Marc Lemort
Alexandre Peltier
author_sort Roland Van Velthoven
collection DOAJ
description Aims. In this study we report our results with storage of cryopreserved semen intended for preservation and subsequent infertility treatment in men with testicular cancer during the last 18 years. Methods. Cryopreserved semen of 523 men with testicular cancer was collected between October 1995 and the end of December 2012. Semen of 34 men (6.5%) was used for fertilization of their partners. They underwent 57 treatment cycles with cryopreserved, fresh, and/or donor sperm. Results. A total of 557 men have decided to freeze their semen before cancer treatment. Seminoma was diagnosed in 283 men (54.1%) and nonseminomatous germ cell tumors in 240 men (45.9%). 34 patients who returned for infertility treatment underwent 46 treatment cycles with cryopreserved sperm. Totally 16 pregnancies were achieved, that is, 34.8% pregnancy rate. Conclusion. The testicular cancer survivors have a good chance of fathering a child by using sperm cryopreserved prior to the oncology treatment, even when it contains only limited number of spermatozoa.
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issn 2090-3111
2090-312X
language English
publishDate 2014-01-01
publisher Wiley
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series Prostate Cancer
spelling doaj-art-d81e5255ee58417088629aa92a7330d22025-08-20T02:20:58ZengWileyProstate Cancer2090-31112090-312X2014-01-01201410.1155/2014/756189756189Primary Zonal High Intensity Focused Ultrasound for Prostate Cancer: Results of a Prospective Phase IIa Feasibility StudyRoland Van Velthoven0Fouad Aoun1Ksenija Limani2Krishna Narahari3Marc Lemort4Alexandre Peltier5Department of Urology, Jules Bordet Institute, 1 Héger-Bordet Street, 1000 Brussels, BelgiumDepartment of Urology, Jules Bordet Institute, 1 Héger-Bordet Street, 1000 Brussels, BelgiumDepartment of Urology, Jules Bordet Institute, 1 Héger-Bordet Street, 1000 Brussels, BelgiumDepartment of Urology, Jules Bordet Institute, 1 Héger-Bordet Street, 1000 Brussels, BelgiumDepartment of Radiology, Jules Bordet Institute, 1 Héger-Bordet Street, 1000 Brussels, BelgiumDepartment of Urology, Jules Bordet Institute, 1 Héger-Bordet Street, 1000 Brussels, BelgiumAims. In this study we report our results with storage of cryopreserved semen intended for preservation and subsequent infertility treatment in men with testicular cancer during the last 18 years. Methods. Cryopreserved semen of 523 men with testicular cancer was collected between October 1995 and the end of December 2012. Semen of 34 men (6.5%) was used for fertilization of their partners. They underwent 57 treatment cycles with cryopreserved, fresh, and/or donor sperm. Results. A total of 557 men have decided to freeze their semen before cancer treatment. Seminoma was diagnosed in 283 men (54.1%) and nonseminomatous germ cell tumors in 240 men (45.9%). 34 patients who returned for infertility treatment underwent 46 treatment cycles with cryopreserved sperm. Totally 16 pregnancies were achieved, that is, 34.8% pregnancy rate. Conclusion. The testicular cancer survivors have a good chance of fathering a child by using sperm cryopreserved prior to the oncology treatment, even when it contains only limited number of spermatozoa.http://dx.doi.org/10.1155/2014/756189
spellingShingle Roland Van Velthoven
Fouad Aoun
Ksenija Limani
Krishna Narahari
Marc Lemort
Alexandre Peltier
Primary Zonal High Intensity Focused Ultrasound for Prostate Cancer: Results of a Prospective Phase IIa Feasibility Study
Prostate Cancer
title Primary Zonal High Intensity Focused Ultrasound for Prostate Cancer: Results of a Prospective Phase IIa Feasibility Study
title_full Primary Zonal High Intensity Focused Ultrasound for Prostate Cancer: Results of a Prospective Phase IIa Feasibility Study
title_fullStr Primary Zonal High Intensity Focused Ultrasound for Prostate Cancer: Results of a Prospective Phase IIa Feasibility Study
title_full_unstemmed Primary Zonal High Intensity Focused Ultrasound for Prostate Cancer: Results of a Prospective Phase IIa Feasibility Study
title_short Primary Zonal High Intensity Focused Ultrasound for Prostate Cancer: Results of a Prospective Phase IIa Feasibility Study
title_sort primary zonal high intensity focused ultrasound for prostate cancer results of a prospective phase iia feasibility study
url http://dx.doi.org/10.1155/2014/756189
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