A new paradigm of islet adaptations in human pregnancy: insights from immunohistochemistry and proteomics
Abstract Physiological changes during pregnancy support foetal growth, including adaptations in pancreatic islets to maintain glucose homeostasis. We investigate these adaptations using rare, high-quality pancreatic tissue from pregnant human donors and matched controls. We profile islets from pregn...
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| Main Authors: | Faheem Seedat, Katie Holden, Simon Davis, Roman Fischer, James Bancroft, Edward Drydale, Neva Kandzija, John A. Todd, Manu Vatish, M. Irina Stefana |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-07-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-025-61852-5 |
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