Tophaceous Gout in the Pancreas: Case Reports and Review of the Literature
We report 3 patients who presented with abnormal pancreatic contents that were initially nondiagnostic but were eventually found to have urate crystal deposition consistent with pancreatic tophaceous gout. Our first case involved an ICU patient who had fever of unknown origin and refractory pancreat...
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| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2022-01-01
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| Series: | Case Reports in Rheumatology |
| Online Access: | http://dx.doi.org/10.1155/2022/3671627 |
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| _version_ | 1832565819026964480 |
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| author | Soo Choi Natalie Voskanian Jeffrey Ramos Katherine H.Y. Nguyen |
| author_facet | Soo Choi Natalie Voskanian Jeffrey Ramos Katherine H.Y. Nguyen |
| author_sort | Soo Choi |
| collection | DOAJ |
| description | We report 3 patients who presented with abnormal pancreatic contents that were initially nondiagnostic but were eventually found to have urate crystal deposition consistent with pancreatic tophaceous gout. Our first case involved an ICU patient who had fever of unknown origin and refractory pancreatic pseudocyst. The other 2 patients presented with abdominal pain associated with a pancreatic mass which mimicked malignancy. After further investigation, we were able to identify pancreatic tophaceous gout as the diagnosis. Initiation of therapy led to resolution of pancreatitis in the first patient and resolution of abdominal pain and decrease in size of a pancreatic mass in the other 2 patients. The recognition of clinical gout involving the pancreas has important implications in the evaluation and care of these patients who are at high risk for tophaceous gout. In addition, the importance of specimen preparation that preserves crystals for viewing is discussed. |
| format | Article |
| id | doaj-art-d805efb00257427ca00ff4382fb9f43d |
| institution | Kabale University |
| issn | 2090-6897 |
| language | English |
| publishDate | 2022-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Rheumatology |
| spelling | doaj-art-d805efb00257427ca00ff4382fb9f43d2025-02-03T01:06:38ZengWileyCase Reports in Rheumatology2090-68972022-01-01202210.1155/2022/3671627Tophaceous Gout in the Pancreas: Case Reports and Review of the LiteratureSoo Choi0Natalie Voskanian1Jeffrey Ramos2Katherine H.Y. Nguyen3University of CaliforniaUniversity of CaliforniaScripps Memorial HospitalUniversity of CaliforniaWe report 3 patients who presented with abnormal pancreatic contents that were initially nondiagnostic but were eventually found to have urate crystal deposition consistent with pancreatic tophaceous gout. Our first case involved an ICU patient who had fever of unknown origin and refractory pancreatic pseudocyst. The other 2 patients presented with abdominal pain associated with a pancreatic mass which mimicked malignancy. After further investigation, we were able to identify pancreatic tophaceous gout as the diagnosis. Initiation of therapy led to resolution of pancreatitis in the first patient and resolution of abdominal pain and decrease in size of a pancreatic mass in the other 2 patients. The recognition of clinical gout involving the pancreas has important implications in the evaluation and care of these patients who are at high risk for tophaceous gout. In addition, the importance of specimen preparation that preserves crystals for viewing is discussed.http://dx.doi.org/10.1155/2022/3671627 |
| spellingShingle | Soo Choi Natalie Voskanian Jeffrey Ramos Katherine H.Y. Nguyen Tophaceous Gout in the Pancreas: Case Reports and Review of the Literature Case Reports in Rheumatology |
| title | Tophaceous Gout in the Pancreas: Case Reports and Review of the Literature |
| title_full | Tophaceous Gout in the Pancreas: Case Reports and Review of the Literature |
| title_fullStr | Tophaceous Gout in the Pancreas: Case Reports and Review of the Literature |
| title_full_unstemmed | Tophaceous Gout in the Pancreas: Case Reports and Review of the Literature |
| title_short | Tophaceous Gout in the Pancreas: Case Reports and Review of the Literature |
| title_sort | tophaceous gout in the pancreas case reports and review of the literature |
| url | http://dx.doi.org/10.1155/2022/3671627 |
| work_keys_str_mv | AT soochoi tophaceousgoutinthepancreascasereportsandreviewoftheliterature AT natalievoskanian tophaceousgoutinthepancreascasereportsandreviewoftheliterature AT jeffreyramos tophaceousgoutinthepancreascasereportsandreviewoftheliterature AT katherinehynguyen tophaceousgoutinthepancreascasereportsandreviewoftheliterature |