Advanced quantification pipeline reveals new spatial and temporal tumor characteristics in preclinical multiple myeloma

Advanced quantification pipeline reveals new spatial and temporal tumor characteristics in preclinical multiple myeloma

Abstract Background Radiological imaging plays an indispensable role in both preclinical and clinical studies of multiple myeloma (MM). However, manual quantification in longitudinal small animal PET/CT is limited by annotator bias, signal artifacts from urinary/fecal excretion, and voxel misalignme...

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Bibliographic Details
Main Authors: Zhixin Sun, Jacqueline M. Godbe, Alexander Zheleznyak, Brad Manion, Junhao Hu, Julie L. Prior, Kathleen Duncan, Ulugbek S. Kamilov, Monica Shokeen
Format: Article
Language:English
Published: SpringerOpen 2025-07-01
Series:EJNMMI Research
Subjects:
Multiple myeloma (MM) imaging
Bone segmentation
PET/CT quantification
Skeletal lesions
Online Access:https://doi.org/10.1186/s13550-025-01291-x
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