Therapeutic Prospects of <i>Undaria pinnatifida</i> Polysaccharides: Extraction, Purification, and Functional Activity

<i>Undaria pinnatifida</i>, an edible brown seaweed that is widely consumed in East Asia, has gained increasing recognition for its health benefits. Among its bioactive compounds, polysaccharides have attracted significant attention due to their diverse biological activity. This review p...

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Main Authors: Kit-Leong Cheong, Wenjie Chen, Min Wang, Saiyi Zhong, Suresh Veeraperumal
Format: Article
Language:English
Published: MDPI AG 2025-04-01
Series:Marine Drugs
Subjects:
Online Access:https://www.mdpi.com/1660-3397/23/4/163
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author Kit-Leong Cheong
Wenjie Chen
Min Wang
Saiyi Zhong
Suresh Veeraperumal
author_facet Kit-Leong Cheong
Wenjie Chen
Min Wang
Saiyi Zhong
Suresh Veeraperumal
author_sort Kit-Leong Cheong
collection DOAJ
description <i>Undaria pinnatifida</i>, an edible brown seaweed that is widely consumed in East Asia, has gained increasing recognition for its health benefits. Among its bioactive compounds, polysaccharides have attracted significant attention due to their diverse biological activity. This review provides a comprehensive overview of recent advancements in the extraction, purification, structural characterization, and bioactivity of <i>U. pinnatifida</i> polysaccharides. We discuss state-of-the-art extraction techniques, including ultrasound-assisted, microwave-assisted, and enzyme-assisted extraction, as well as purification strategies such as membrane separation and chromatographic methods. Furthermore, we highlight their potential biological activity, including antioxidant, immunomodulatory, anticancer, gut health-promoting, and anti-hyperglycemic effects, along with their underlying mechanisms of action. By summarizing the latest research, this review aims to provide valuable insights into the development and application of <i>U. pinnatifida</i> polysaccharides in functional foods and pharmaceuticals.
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series Marine Drugs
spelling doaj-art-d7f2fb3b07d84ad19f7a2687f187e6c92025-08-20T02:18:19ZengMDPI AGMarine Drugs1660-33972025-04-0123416310.3390/md23040163Therapeutic Prospects of <i>Undaria pinnatifida</i> Polysaccharides: Extraction, Purification, and Functional ActivityKit-Leong Cheong0Wenjie Chen1Min Wang2Saiyi Zhong3Suresh Veeraperumal4Guangdong Provincial Key Laboratory of Aquatic Product Processing and Safety, College of Food Science and Technology, Guangdong Ocean University, Zhanjiang 524088, ChinaGuangdong Provincial Key Laboratory of Aquatic Product Processing and Safety, College of Food Science and Technology, Guangdong Ocean University, Zhanjiang 524088, ChinaCollege of Coastal Agriculture Sciences, Guangdong Ocean University, Zhanjiang 524088, ChinaGuangdong Provincial Key Laboratory of Aquatic Product Processing and Safety, College of Food Science and Technology, Guangdong Ocean University, Zhanjiang 524088, ChinaDepartment of Biology, College of Science, Shantou University, Shantou 515063, China<i>Undaria pinnatifida</i>, an edible brown seaweed that is widely consumed in East Asia, has gained increasing recognition for its health benefits. Among its bioactive compounds, polysaccharides have attracted significant attention due to their diverse biological activity. This review provides a comprehensive overview of recent advancements in the extraction, purification, structural characterization, and bioactivity of <i>U. pinnatifida</i> polysaccharides. We discuss state-of-the-art extraction techniques, including ultrasound-assisted, microwave-assisted, and enzyme-assisted extraction, as well as purification strategies such as membrane separation and chromatographic methods. Furthermore, we highlight their potential biological activity, including antioxidant, immunomodulatory, anticancer, gut health-promoting, and anti-hyperglycemic effects, along with their underlying mechanisms of action. By summarizing the latest research, this review aims to provide valuable insights into the development and application of <i>U. pinnatifida</i> polysaccharides in functional foods and pharmaceuticals.https://www.mdpi.com/1660-3397/23/4/163<i>Undaria pinnatifida</i>polysaccharidesisolationpurificationbiological activity
spellingShingle Kit-Leong Cheong
Wenjie Chen
Min Wang
Saiyi Zhong
Suresh Veeraperumal
Therapeutic Prospects of <i>Undaria pinnatifida</i> Polysaccharides: Extraction, Purification, and Functional Activity
Marine Drugs
<i>Undaria pinnatifida</i>
polysaccharides
isolation
purification
biological activity
title Therapeutic Prospects of <i>Undaria pinnatifida</i> Polysaccharides: Extraction, Purification, and Functional Activity
title_full Therapeutic Prospects of <i>Undaria pinnatifida</i> Polysaccharides: Extraction, Purification, and Functional Activity
title_fullStr Therapeutic Prospects of <i>Undaria pinnatifida</i> Polysaccharides: Extraction, Purification, and Functional Activity
title_full_unstemmed Therapeutic Prospects of <i>Undaria pinnatifida</i> Polysaccharides: Extraction, Purification, and Functional Activity
title_short Therapeutic Prospects of <i>Undaria pinnatifida</i> Polysaccharides: Extraction, Purification, and Functional Activity
title_sort therapeutic prospects of i undaria pinnatifida i polysaccharides extraction purification and functional activity
topic <i>Undaria pinnatifida</i>
polysaccharides
isolation
purification
biological activity
url https://www.mdpi.com/1660-3397/23/4/163
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AT minwang therapeuticprospectsofiundariapinnatifidaipolysaccharidesextractionpurificationandfunctionalactivity
AT saiyizhong therapeuticprospectsofiundariapinnatifidaipolysaccharidesextractionpurificationandfunctionalactivity
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