Late-onset Group B Streptococcal Meningitis in a Neonate With Early Antibiotic Prophylaxis
An otherwise healthy female baby who had received early postnatal antibiotic prophylaxis because of maternal vaginal group B streptococcal (GBS) colonization died of late-onset GBS meningitis. GBS was isolated from blood and cerebrospinal fluid. Genotyping using pulsed-field gel electrophoresis conf...
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| Format: | Article |
| Language: | English |
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Elsevier
2010-08-01
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| Series: | Pediatrics and Neonatology |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S1875957210600460 |
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| author | Ting-Jung Ko Wu-Shiun Hsieh Po-Ren Hsueh Hung-Chieh Chou Chun-Yi Lu |
| author_facet | Ting-Jung Ko Wu-Shiun Hsieh Po-Ren Hsueh Hung-Chieh Chou Chun-Yi Lu |
| author_sort | Ting-Jung Ko |
| collection | DOAJ |
| description | An otherwise healthy female baby who had received early postnatal antibiotic prophylaxis because of maternal vaginal group B streptococcal (GBS) colonization died of late-onset GBS meningitis. GBS was isolated from blood and cerebrospinal fluid. Genotyping using pulsed-field gel electrophoresis confirmed that the GBS isolates from the patient were identical to those from her mother's vagina. Susceptibility tests demonstrated no antibiotic resistance. This report provides additional microbiologic evidence indicating that early postnatal antibiotic prophylaxis is not effective in preventing late-onset GBS infections in neonates born to mothers with GBS colonization. |
| format | Article |
| id | doaj-art-d7e6fddfbd3045faa7e7389f0f8c4b15 |
| institution | OA Journals |
| issn | 1875-9572 |
| language | English |
| publishDate | 2010-08-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Pediatrics and Neonatology |
| spelling | doaj-art-d7e6fddfbd3045faa7e7389f0f8c4b152025-08-20T02:11:19ZengElsevierPediatrics and Neonatology1875-95722010-08-0151424224410.1016/S1875-9572(10)60046-0Late-onset Group B Streptococcal Meningitis in a Neonate With Early Antibiotic ProphylaxisTing-Jung Ko0Wu-Shiun Hsieh1Po-Ren Hsueh2Hung-Chieh Chou3Chun-Yi Lu4Department of Pediatrics, National Taiwan University Hospital, Taipei, TaiwanDepartment of Pediatrics, National Taiwan University Hospital, Taipei, TaiwanDepartment of Laboratory Medicine, National Taiwan University Hospital, Taipei, TaiwanDepartment of Pediatrics, National Taiwan University Hospital, Taipei, TaiwanDepartment of Pediatrics, National Taiwan University Hospital, Taipei, TaiwanAn otherwise healthy female baby who had received early postnatal antibiotic prophylaxis because of maternal vaginal group B streptococcal (GBS) colonization died of late-onset GBS meningitis. GBS was isolated from blood and cerebrospinal fluid. Genotyping using pulsed-field gel electrophoresis confirmed that the GBS isolates from the patient were identical to those from her mother's vagina. Susceptibility tests demonstrated no antibiotic resistance. This report provides additional microbiologic evidence indicating that early postnatal antibiotic prophylaxis is not effective in preventing late-onset GBS infections in neonates born to mothers with GBS colonization.http://www.sciencedirect.com/science/article/pii/S1875957210600460group B streptococcuslate-onsetmeningitisprophylaxis |
| spellingShingle | Ting-Jung Ko Wu-Shiun Hsieh Po-Ren Hsueh Hung-Chieh Chou Chun-Yi Lu Late-onset Group B Streptococcal Meningitis in a Neonate With Early Antibiotic Prophylaxis Pediatrics and Neonatology group B streptococcus late-onset meningitis prophylaxis |
| title | Late-onset Group B Streptococcal Meningitis in a Neonate With Early Antibiotic Prophylaxis |
| title_full | Late-onset Group B Streptococcal Meningitis in a Neonate With Early Antibiotic Prophylaxis |
| title_fullStr | Late-onset Group B Streptococcal Meningitis in a Neonate With Early Antibiotic Prophylaxis |
| title_full_unstemmed | Late-onset Group B Streptococcal Meningitis in a Neonate With Early Antibiotic Prophylaxis |
| title_short | Late-onset Group B Streptococcal Meningitis in a Neonate With Early Antibiotic Prophylaxis |
| title_sort | late onset group b streptococcal meningitis in a neonate with early antibiotic prophylaxis |
| topic | group B streptococcus late-onset meningitis prophylaxis |
| url | http://www.sciencedirect.com/science/article/pii/S1875957210600460 |
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