Effect of Dual‐Site Non‐Invasive Brain Stimulation on Upper‐Limb Function After Stroke: A Systematic Review and Meta‐Analysis
ABSTRACT Background Non‐invasive brain stimulation (NIBS) has attracted significant attention as it has been proven to be effective in facilitating upper limb motor recovery in patients with stroke. This meta‐analysis evaluates the efficacy of dual‐site non‐invasive brain stimulation (DS‐NIBS) in im...
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| Format: | Article |
| Language: | English |
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Wiley
2024-11-01
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| Series: | Brain and Behavior |
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| Online Access: | https://doi.org/10.1002/brb3.70145 |
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| author | Meng Ren Jingjing Xu Wenjing Wang Lexian Shen Chaojie Wang Haoyang Liu Lu Chen Chanjing Liu Yongheng Tang Jiening Wang Tiantian Liu |
| author_facet | Meng Ren Jingjing Xu Wenjing Wang Lexian Shen Chaojie Wang Haoyang Liu Lu Chen Chanjing Liu Yongheng Tang Jiening Wang Tiantian Liu |
| author_sort | Meng Ren |
| collection | DOAJ |
| description | ABSTRACT Background Non‐invasive brain stimulation (NIBS) has attracted significant attention as it has been proven to be effective in facilitating upper limb motor recovery in patients with stroke. This meta‐analysis evaluates the efficacy of dual‐site non‐invasive brain stimulation (DS‐NIBS) in improving upper extremity motor function after stroke. Methods A PRISMA systematic search was conducted for randomized controlled trials. Two authors independently extracted data, and the quality of included studies was assessed. Results Ten studies were included in the current review. DS‐NIBS demonstrated a significant effect on upper extremity motor function impairment. However, only two studies showed no clear effects of DS‐tDCS on upper extremity motor function after stroke. Due to the limited number of studies, the effects of DS‐NIBS remain inconclusive. Finding This review found evidence for the relatively higher efficacy of DS‐NIBS on post‐stroke upper extremity motor function impairment, compared to the sham and SS‐NIBS. Additionally, DS‐TMS was found to generate better improvement than DS‐tDCS. |
| format | Article |
| id | doaj-art-d7e67e6cb7484f3b8baa420dd5e60d4e |
| institution | OA Journals |
| issn | 2162-3279 |
| language | English |
| publishDate | 2024-11-01 |
| publisher | Wiley |
| record_format | Article |
| series | Brain and Behavior |
| spelling | doaj-art-d7e67e6cb7484f3b8baa420dd5e60d4e2025-08-20T01:52:53ZengWileyBrain and Behavior2162-32792024-11-011411n/an/a10.1002/brb3.70145Effect of Dual‐Site Non‐Invasive Brain Stimulation on Upper‐Limb Function After Stroke: A Systematic Review and Meta‐AnalysisMeng Ren0Jingjing Xu1Wenjing Wang2Lexian Shen3Chaojie Wang4Haoyang Liu5Lu Chen6Chanjing Liu7Yongheng Tang8Jiening Wang9Tiantian Liu10RainbowFish Rehabilitation and Nursing SchoolHangzhou Vocational and Technical CollegeHangzhou ChinaAthletic rehabilitation Teaching and Research Office, School of Exercise and HealthGuangzhou Sport UniversityGuangzhouChinaSeventh People's Hospital Affiliated to Shanghai University of Traditional Chinese MedicineShanghaiChinaSchool of Foreign LanguagesShanghai Jiao Tong UniversityShanghaiChinaAcupuncture and Moxibustion Massage CollegeLiaoning University of Traditional Chinese MedicineShenyang ChinaRainbowFish Rehabilitation and Nursing SchoolHangzhou Vocational and Technical CollegeHangzhou ChinaRainbowFish Rehabilitation and Nursing SchoolHangzhou Vocational and Technical CollegeHangzhou ChinaRainbowFish Rehabilitation and Nursing SchoolHangzhou Vocational and Technical CollegeHangzhou ChinaRainbowFish Rehabilitation and Nursing SchoolHangzhou Vocational and Technical CollegeHangzhou ChinaSeventh People's Hospital Affiliated to Shanghai University of Traditional Chinese MedicineShanghaiChinaSeventh People's Hospital Affiliated to Shanghai University of Traditional Chinese MedicineShanghaiChinaABSTRACT Background Non‐invasive brain stimulation (NIBS) has attracted significant attention as it has been proven to be effective in facilitating upper limb motor recovery in patients with stroke. This meta‐analysis evaluates the efficacy of dual‐site non‐invasive brain stimulation (DS‐NIBS) in improving upper extremity motor function after stroke. Methods A PRISMA systematic search was conducted for randomized controlled trials. Two authors independently extracted data, and the quality of included studies was assessed. Results Ten studies were included in the current review. DS‐NIBS demonstrated a significant effect on upper extremity motor function impairment. However, only two studies showed no clear effects of DS‐tDCS on upper extremity motor function after stroke. Due to the limited number of studies, the effects of DS‐NIBS remain inconclusive. Finding This review found evidence for the relatively higher efficacy of DS‐NIBS on post‐stroke upper extremity motor function impairment, compared to the sham and SS‐NIBS. Additionally, DS‐TMS was found to generate better improvement than DS‐tDCS.https://doi.org/10.1002/brb3.70145meta‐analysisstroketranscranial direct current stimulationtranscranial magnetic stimulationupper extremity |
| spellingShingle | Meng Ren Jingjing Xu Wenjing Wang Lexian Shen Chaojie Wang Haoyang Liu Lu Chen Chanjing Liu Yongheng Tang Jiening Wang Tiantian Liu Effect of Dual‐Site Non‐Invasive Brain Stimulation on Upper‐Limb Function After Stroke: A Systematic Review and Meta‐Analysis Brain and Behavior meta‐analysis stroke transcranial direct current stimulation transcranial magnetic stimulation upper extremity |
| title | Effect of Dual‐Site Non‐Invasive Brain Stimulation on Upper‐Limb Function After Stroke: A Systematic Review and Meta‐Analysis |
| title_full | Effect of Dual‐Site Non‐Invasive Brain Stimulation on Upper‐Limb Function After Stroke: A Systematic Review and Meta‐Analysis |
| title_fullStr | Effect of Dual‐Site Non‐Invasive Brain Stimulation on Upper‐Limb Function After Stroke: A Systematic Review and Meta‐Analysis |
| title_full_unstemmed | Effect of Dual‐Site Non‐Invasive Brain Stimulation on Upper‐Limb Function After Stroke: A Systematic Review and Meta‐Analysis |
| title_short | Effect of Dual‐Site Non‐Invasive Brain Stimulation on Upper‐Limb Function After Stroke: A Systematic Review and Meta‐Analysis |
| title_sort | effect of dual site non invasive brain stimulation on upper limb function after stroke a systematic review and meta analysis |
| topic | meta‐analysis stroke transcranial direct current stimulation transcranial magnetic stimulation upper extremity |
| url | https://doi.org/10.1002/brb3.70145 |
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