Novel transcripts of EMT driving the malignant transformation of oral submucous fibrosis

Novel transcripts of EMT driving the malignant transformation of oral submucous fibrosis

Abstract Oral submucous fibrosis (OSF) is a chronic, progressive, and fibrotic condition of the oral mucosa that carries an elevated risk of malignant transformation. We aimed to identify and validate novel genes associated with the regulation of epithelial-to-mesenchymal transition (EMT) in OSF. Ge...

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Bibliographic Details
Main Authors: Smitha Sammith Shetty, Kanaka Sai Ram Padam, Mohit Sharma, Adarsh Kudva, Pratik Patel, Raghu Radhakrishnan
Format: Article
Language:English
Published: Nature Portfolio 2025-01-01
Series:Scientific Reports
Subjects:
Oral squamous cell carcinoma
Oral submucous fibrosis
Candidate genes
EMT
In-silico analysis
Proteomics
Online Access:https://doi.org/10.1038/s41598-025-87790-2
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