Baseline Findings of an HIV Incidence Cohort Study to Prepare for Future HIV Prevention Clinical Trials in Kisumu, Kenya

Introduction: In an analysis of baseline findings of an HIV incidence cohort study, an assessment was made of HIV prevalence among persons presenting for enrollment and any differences in demographic characteristics between persons not enrolled compared to those enrolled.  We also described and comp...

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Main Authors: Wairimu Chege, Sherri L Pals, Eleanor McLellan-Lemal, Sanjyot Shinde, Monicah Nyambura, Frederick O Otieno, Deborah A Gust, Robert T Chen, Timothy Thomas
Format: Article
Language:English
Published: The Journal of Infection in Developing Countries 2012-12-01
Series:Journal of Infection in Developing Countries
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Online Access:https://jidc.org/index.php/journal/article/view/2636
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author Wairimu Chege
Sherri L Pals
Eleanor McLellan-Lemal
Sanjyot Shinde
Monicah Nyambura
Frederick O Otieno
Deborah A Gust
Robert T Chen
Timothy Thomas
author_facet Wairimu Chege
Sherri L Pals
Eleanor McLellan-Lemal
Sanjyot Shinde
Monicah Nyambura
Frederick O Otieno
Deborah A Gust
Robert T Chen
Timothy Thomas
author_sort Wairimu Chege
collection DOAJ
description Introduction: In an analysis of baseline findings of an HIV incidence cohort study, an assessment was made of HIV prevalence among persons presenting for enrollment and any differences in demographic characteristics between persons not enrolled compared to those enrolled.  We also described and compared HIV risk behaviors in males and females enrolled in the study. Methodology: A computer-assisted survey was administered to collect baseline demographic and HIV risk data from 1,277 men and women aged 18-34 years. Testing for HIV and other sexually transmitted infections (STI) was conducted.  Out of 1,277 persons prescreened for eligibility, 625 were enrolled. Results: HIV prevalence of all persons who completed screening was 14.8% (females: 21.1%; males: 8.1%).  The odds of being enrolled in the study were higher for persons 18-24 years compared to those 30-34 years of age [adjusted odds ratio (AOR)=2.18, CI=1.13, 4.21] and males compared to females [AOR=2.07, CI=1.43, 2.99].  Among those enrolled in the study, the most prevalent HIV risk behaviors were unprotected sex (49%), alcohol use (45%), and transactional sex (30%) in the last three months. Compared to females, a significantly greater proportion of males reported using any alcohol or recreational drug in the last three months, a history of oral sex, sex with partner other than a spouse or main partner, ever having a blood transfusion, ever being treated for an STI, and having knowledge of their last HIV test result. Conclusion: The Kisumu Field Station successfully recruited individuals with HIV risk characteristics for the HIV incidence cohort study.
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spelling doaj-art-d7d38dabe03a4258830f76b86e240fb72025-08-20T02:57:14ZengThe Journal of Infection in Developing CountriesJournal of Infection in Developing Countries1972-26802012-12-0161210.3855/jidc.2636Baseline Findings of an HIV Incidence Cohort Study to Prepare for Future HIV Prevention Clinical Trials in Kisumu, KenyaWairimu Chege0Sherri L Pals1Eleanor McLellan-Lemal2Sanjyot Shinde3Monicah Nyambura4Frederick O Otieno5Deborah A Gust6Robert T Chen7Timothy Thomas8Centers for Disease Control and Prevention (CDC), Division of HIV/AIDS Prevention, Atlanta, United StatesCenters for Disease Control and Prevention (CDC), Division of HIV/AIDS Prevention, Atlanta, United StatesCenters for Disease Control and Prevention (CDC), Division of HIV/AIDS Prevention, Atlanta, United StatesCenters for Disease Control and Prevention (CDC), Division of HIV/AIDS Prevention, Atlanta, United StatesCenter for Global Health Research, Kenya Medical Research Institute (KEMRI)/CDC Research and Public Health Collaboration, Kisumu, KenyaCenter for Global Health Research, Kenya Medical Research Institute (KEMRI)/CDC Research and Public Health Collaboration, Kisumu, KenyaCenters for Disease Control and Prevention (CDC), Division of HIV/AIDS Prevention, Atlanta, United StatesCenters for Disease Control and Prevention (CDC), Division of HIV/AIDS Prevention, Atlanta, United StatesCenters for Disease Control and Prevention (CDC), Division of HIV/AIDS Prevention, Atlanta, United StatesIntroduction: In an analysis of baseline findings of an HIV incidence cohort study, an assessment was made of HIV prevalence among persons presenting for enrollment and any differences in demographic characteristics between persons not enrolled compared to those enrolled.  We also described and compared HIV risk behaviors in males and females enrolled in the study. Methodology: A computer-assisted survey was administered to collect baseline demographic and HIV risk data from 1,277 men and women aged 18-34 years. Testing for HIV and other sexually transmitted infections (STI) was conducted.  Out of 1,277 persons prescreened for eligibility, 625 were enrolled. Results: HIV prevalence of all persons who completed screening was 14.8% (females: 21.1%; males: 8.1%).  The odds of being enrolled in the study were higher for persons 18-24 years compared to those 30-34 years of age [adjusted odds ratio (AOR)=2.18, CI=1.13, 4.21] and males compared to females [AOR=2.07, CI=1.43, 2.99].  Among those enrolled in the study, the most prevalent HIV risk behaviors were unprotected sex (49%), alcohol use (45%), and transactional sex (30%) in the last three months. Compared to females, a significantly greater proportion of males reported using any alcohol or recreational drug in the last three months, a history of oral sex, sex with partner other than a spouse or main partner, ever having a blood transfusion, ever being treated for an STI, and having knowledge of their last HIV test result. Conclusion: The Kisumu Field Station successfully recruited individuals with HIV risk characteristics for the HIV incidence cohort study. https://jidc.org/index.php/journal/article/view/2636HIVKenyagender differencesrisk behaviors
spellingShingle Wairimu Chege
Sherri L Pals
Eleanor McLellan-Lemal
Sanjyot Shinde
Monicah Nyambura
Frederick O Otieno
Deborah A Gust
Robert T Chen
Timothy Thomas
Baseline Findings of an HIV Incidence Cohort Study to Prepare for Future HIV Prevention Clinical Trials in Kisumu, Kenya
Journal of Infection in Developing Countries
HIV
Kenya
gender differences
risk behaviors
title Baseline Findings of an HIV Incidence Cohort Study to Prepare for Future HIV Prevention Clinical Trials in Kisumu, Kenya
title_full Baseline Findings of an HIV Incidence Cohort Study to Prepare for Future HIV Prevention Clinical Trials in Kisumu, Kenya
title_fullStr Baseline Findings of an HIV Incidence Cohort Study to Prepare for Future HIV Prevention Clinical Trials in Kisumu, Kenya
title_full_unstemmed Baseline Findings of an HIV Incidence Cohort Study to Prepare for Future HIV Prevention Clinical Trials in Kisumu, Kenya
title_short Baseline Findings of an HIV Incidence Cohort Study to Prepare for Future HIV Prevention Clinical Trials in Kisumu, Kenya
title_sort baseline findings of an hiv incidence cohort study to prepare for future hiv prevention clinical trials in kisumu kenya
topic HIV
Kenya
gender differences
risk behaviors
url https://jidc.org/index.php/journal/article/view/2636
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