Sweet Syndrome due to Myelodysplastic Syndrome: Possible Therapeutic Role of Intravenous Immunoglobulin in Addition to Standard Treatment

We report an 82-year-old lady who developed sudden onset nodular and erythematous lesions and neutrophilia following an episode of urinary tract infection. Skin biopsy confirmed the diagnosis of Sweet syndrome. Response to the use of prednisolone alone was not satisfactory. The skin lesions however...

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Main Authors: Harry H. S. Gill, Anskar Y. H. Leung, N. J. Trendell-Smith, C. K. Yeung, Raymond Liang
Format: Article
Language:English
Published: Wiley 2010-01-01
Series:Advances in Hematology
Online Access:http://dx.doi.org/10.1155/2010/328316
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author Harry H. S. Gill
Anskar Y. H. Leung
N. J. Trendell-Smith
C. K. Yeung
Raymond Liang
author_facet Harry H. S. Gill
Anskar Y. H. Leung
N. J. Trendell-Smith
C. K. Yeung
Raymond Liang
author_sort Harry H. S. Gill
collection DOAJ
description We report an 82-year-old lady who developed sudden onset nodular and erythematous lesions and neutrophilia following an episode of urinary tract infection. Skin biopsy confirmed the diagnosis of Sweet syndrome. Response to the use of prednisolone alone was not satisfactory. The skin lesions however showed a sustained response to the regular use of intravenous immunoglobulin (IVIG) and prednisolone was slowly weaned off. Our case highlights the possible therapeutic role of IVIG in managing this condition.
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institution Kabale University
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language English
publishDate 2010-01-01
publisher Wiley
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series Advances in Hematology
spelling doaj-art-d7d0ab534ed74e3c9ba682c31556caca2025-02-03T01:31:18ZengWileyAdvances in Hematology1687-91041687-91122010-01-01201010.1155/2010/328316328316Sweet Syndrome due to Myelodysplastic Syndrome: Possible Therapeutic Role of Intravenous Immunoglobulin in Addition to Standard TreatmentHarry H. S. Gill0Anskar Y. H. Leung1N. J. Trendell-Smith2C. K. Yeung3Raymond Liang4Division of Haematology, Medical Oncology and Bone Marrow Transplantation, Department of Medicine, Queen Mary Hospital, The University of Hong Kong, Pokfulam, Hong KongDivision of Haematology, Medical Oncology and Bone Marrow Transplantation, Department of Medicine, Queen Mary Hospital, The University of Hong Kong, Pokfulam, Hong KongDepartment of Pathology, Queen Mary Hospital, Pokfulam, Hong KongDivision of Dermatology, Department of Medicine, The University of Hong Kong, Queen Mary Hospital, Pokfulam, Hong KongDivision of Haematology, Medical Oncology and Bone Marrow Transplantation, Department of Medicine, Queen Mary Hospital, The University of Hong Kong, Pokfulam, Hong KongWe report an 82-year-old lady who developed sudden onset nodular and erythematous lesions and neutrophilia following an episode of urinary tract infection. Skin biopsy confirmed the diagnosis of Sweet syndrome. Response to the use of prednisolone alone was not satisfactory. The skin lesions however showed a sustained response to the regular use of intravenous immunoglobulin (IVIG) and prednisolone was slowly weaned off. Our case highlights the possible therapeutic role of IVIG in managing this condition.http://dx.doi.org/10.1155/2010/328316
spellingShingle Harry H. S. Gill
Anskar Y. H. Leung
N. J. Trendell-Smith
C. K. Yeung
Raymond Liang
Sweet Syndrome due to Myelodysplastic Syndrome: Possible Therapeutic Role of Intravenous Immunoglobulin in Addition to Standard Treatment
Advances in Hematology
title Sweet Syndrome due to Myelodysplastic Syndrome: Possible Therapeutic Role of Intravenous Immunoglobulin in Addition to Standard Treatment
title_full Sweet Syndrome due to Myelodysplastic Syndrome: Possible Therapeutic Role of Intravenous Immunoglobulin in Addition to Standard Treatment
title_fullStr Sweet Syndrome due to Myelodysplastic Syndrome: Possible Therapeutic Role of Intravenous Immunoglobulin in Addition to Standard Treatment
title_full_unstemmed Sweet Syndrome due to Myelodysplastic Syndrome: Possible Therapeutic Role of Intravenous Immunoglobulin in Addition to Standard Treatment
title_short Sweet Syndrome due to Myelodysplastic Syndrome: Possible Therapeutic Role of Intravenous Immunoglobulin in Addition to Standard Treatment
title_sort sweet syndrome due to myelodysplastic syndrome possible therapeutic role of intravenous immunoglobulin in addition to standard treatment
url http://dx.doi.org/10.1155/2010/328316
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