Control of White Spot Lesion Adjacent to Orthodontic Bracket with Use of Fluoride Varnish or Chlorhexidine Gel

The aims of this study were to compare the effectiveness of fluoride varnish and chlorhexidine gel in controlling white spot lesions (WSLs) adjacent to orthodontic brackets and to compare the ability of Quantitative Light-Induced Fluorescence (QLF) to measure mineral uptake with that of transverse m...

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Main Authors: Manuel Restrepo, Diego G. Bussaneli, Fabiano Jeremias, Rita C. L. Cordeiro, Ana C. Magalhães, Denise M. Palomari Spolidorio, Lourdes Santos-Pinto
Format: Article
Language:English
Published: Wiley 2015-01-01
Series:The Scientific World Journal
Online Access:http://dx.doi.org/10.1155/2015/218452
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author Manuel Restrepo
Diego G. Bussaneli
Fabiano Jeremias
Rita C. L. Cordeiro
Ana C. Magalhães
Denise M. Palomari Spolidorio
Lourdes Santos-Pinto
author_facet Manuel Restrepo
Diego G. Bussaneli
Fabiano Jeremias
Rita C. L. Cordeiro
Ana C. Magalhães
Denise M. Palomari Spolidorio
Lourdes Santos-Pinto
author_sort Manuel Restrepo
collection DOAJ
description The aims of this study were to compare the effectiveness of fluoride varnish and chlorhexidine gel in controlling white spot lesions (WSLs) adjacent to orthodontic brackets and to compare the ability of Quantitative Light-Induced Fluorescence (QLF) to measure mineral uptake with that of transverse microradiography (TMR). Thirty premolars with artificially induced WSLs were randomly assigned to three groups: (1) two applications of 5% NaF-varnish (F), with one-week interval, (2) two applications of 2% chlorhexidine gel (CHX), with one-week interval, and (3) control (CO), no treatment. QLF was used to measure changes in fluorescence before and after caries induction, 1 week after each application and 1, 2, and 3 months after the last application of F or CHX. TMR was performed to quantify lesion depth and mineral content after caries induction to evaluate the effects of F, CHX, and CO 3 months after the last application of agents. The data were analyzed by repeated measures ANOVA and Tukey’s test. All treatments increased the mineral content during the experimental period; however, F induced faster remineralization than CHX. The correlation between QLF and TMR was significantly moderate. Two applications of fluoride varnish or 2% chlorhexidine gel at one-week intervals were effective in controlling WSLs.
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spelling doaj-art-d7ca941d76fb402bb00ae045401a832a2025-02-03T00:59:57ZengWileyThe Scientific World Journal2356-61401537-744X2015-01-01201510.1155/2015/218452218452Control of White Spot Lesion Adjacent to Orthodontic Bracket with Use of Fluoride Varnish or Chlorhexidine GelManuel Restrepo0Diego G. Bussaneli1Fabiano Jeremias2Rita C. L. Cordeiro3Ana C. Magalhães4Denise M. Palomari Spolidorio5Lourdes Santos-Pinto6Department of Orthodontics and Pediatric Dentistry, Araraquara School of Dentistry, Universidade Estadual Paulista (Unesp), Rua Humaitá 1680, 14801-903 Araraquara, SP, BrazilDepartment of Orthodontics and Pediatric Dentistry, Araraquara School of Dentistry, Universidade Estadual Paulista (Unesp), Rua Humaitá 1680, 14801-903 Araraquara, SP, BrazilDepartment of Orthodontics and Pediatric Dentistry, Araraquara School of Dentistry, Universidade Estadual Paulista (Unesp), Rua Humaitá 1680, 14801-903 Araraquara, SP, BrazilDepartment of Orthodontics and Pediatric Dentistry, Araraquara School of Dentistry, Universidade Estadual Paulista (Unesp), Rua Humaitá 1680, 14801-903 Araraquara, SP, BrazilDepartment of Biological Sciences, Bauru School of Dentistry, University of São Paulo (USP), Alameda Octávio Pinheiro Brisolla 9-75, 17012-191 Bauru, SP, BrazilDepartment of Physiology and Pathology, Araraquara School of Dentistry, Universidade Estadual Paulista (Unesp), Rua Humaitá 1680, 14801-903 Araraquara, SP, BrazilDepartment of Orthodontics and Pediatric Dentistry, Araraquara School of Dentistry, Universidade Estadual Paulista (Unesp), Rua Humaitá 1680, 14801-903 Araraquara, SP, BrazilThe aims of this study were to compare the effectiveness of fluoride varnish and chlorhexidine gel in controlling white spot lesions (WSLs) adjacent to orthodontic brackets and to compare the ability of Quantitative Light-Induced Fluorescence (QLF) to measure mineral uptake with that of transverse microradiography (TMR). Thirty premolars with artificially induced WSLs were randomly assigned to three groups: (1) two applications of 5% NaF-varnish (F), with one-week interval, (2) two applications of 2% chlorhexidine gel (CHX), with one-week interval, and (3) control (CO), no treatment. QLF was used to measure changes in fluorescence before and after caries induction, 1 week after each application and 1, 2, and 3 months after the last application of F or CHX. TMR was performed to quantify lesion depth and mineral content after caries induction to evaluate the effects of F, CHX, and CO 3 months after the last application of agents. The data were analyzed by repeated measures ANOVA and Tukey’s test. All treatments increased the mineral content during the experimental period; however, F induced faster remineralization than CHX. The correlation between QLF and TMR was significantly moderate. Two applications of fluoride varnish or 2% chlorhexidine gel at one-week intervals were effective in controlling WSLs.http://dx.doi.org/10.1155/2015/218452
spellingShingle Manuel Restrepo
Diego G. Bussaneli
Fabiano Jeremias
Rita C. L. Cordeiro
Ana C. Magalhães
Denise M. Palomari Spolidorio
Lourdes Santos-Pinto
Control of White Spot Lesion Adjacent to Orthodontic Bracket with Use of Fluoride Varnish or Chlorhexidine Gel
The Scientific World Journal
title Control of White Spot Lesion Adjacent to Orthodontic Bracket with Use of Fluoride Varnish or Chlorhexidine Gel
title_full Control of White Spot Lesion Adjacent to Orthodontic Bracket with Use of Fluoride Varnish or Chlorhexidine Gel
title_fullStr Control of White Spot Lesion Adjacent to Orthodontic Bracket with Use of Fluoride Varnish or Chlorhexidine Gel
title_full_unstemmed Control of White Spot Lesion Adjacent to Orthodontic Bracket with Use of Fluoride Varnish or Chlorhexidine Gel
title_short Control of White Spot Lesion Adjacent to Orthodontic Bracket with Use of Fluoride Varnish or Chlorhexidine Gel
title_sort control of white spot lesion adjacent to orthodontic bracket with use of fluoride varnish or chlorhexidine gel
url http://dx.doi.org/10.1155/2015/218452
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