What an Interventionalist Needs to Know About MI with Non-obstructive Coronary Arteries
MI with non-obstructive coronary arteries (MINOCA) is caused by a heterogeneous group of vascular or myocardial disorders. MINOCA occurs in 5–15% of patients presenting with acute ST-segment elevation MI or non-ST segment elevation MI and prognosis is impaired. The diagnosis of MINOCA is made during...
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| Format: | Article |
| Language: | English |
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Radcliffe Medical Media
2021-06-01
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| Series: | Interventional Cardiology: Reviews, Research, Resources |
| Online Access: | https://icrjournal.com/articleindex/icr.2021.10 |
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| author | Robert Sykes Daniel Doherty Kenneth Mangion Andrew Morrow Colin Berry |
| author_facet | Robert Sykes Daniel Doherty Kenneth Mangion Andrew Morrow Colin Berry |
| author_sort | Robert Sykes |
| collection | DOAJ |
| description | MI with non-obstructive coronary arteries (MINOCA) is caused by a heterogeneous group of vascular or myocardial disorders. MINOCA occurs in 5–15% of patients presenting with acute ST-segment elevation MI or non-ST segment elevation MI and prognosis is impaired. The diagnosis of MINOCA is made during coronary angiography following acute MI, where there is no stenosis ≥50% present in an infarct-related epicardial artery and no overt systemic aetiology for the presentation. Accurate diagnosis and subsequent management require the appropriate utilisation of intravascular imaging, coronary function testing and subsequent imaging to assess for myocardial disorders without coronary involvement. Although plaque-related MINOCA is currently managed with empirical secondary prevention strategies, there remains an unmet therapeutic need for targeted and evidence-based therapy for MINOCA patients and increased awareness of the recommended diagnostic pathway. |
| format | Article |
| id | doaj-art-d7b1cf4514ae4df7ac47249d3c48bfdf |
| institution | OA Journals |
| issn | 1756-1477 1756-1485 |
| language | English |
| publishDate | 2021-06-01 |
| publisher | Radcliffe Medical Media |
| record_format | Article |
| series | Interventional Cardiology: Reviews, Research, Resources |
| spelling | doaj-art-d7b1cf4514ae4df7ac47249d3c48bfdf2025-08-20T02:37:41ZengRadcliffe Medical MediaInterventional Cardiology: Reviews, Research, Resources1756-14771756-14852021-06-011610.15420/icr.2021.10What an Interventionalist Needs to Know About MI with Non-obstructive Coronary ArteriesRobert Sykes0Daniel Doherty1Kenneth Mangion2Andrew Morrow3Colin Berry4West of Scotland Heart and Lung Centre, Golden Jubilee National Hospital, Glasgow, UK; Institute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, UKWest of Scotland Heart and Lung Centre, Golden Jubilee National Hospital, Glasgow, UKWest of Scotland Heart and Lung Centre, Golden Jubilee National Hospital, Glasgow, UK; Institute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, UK; Department of Cardiology, Queen Elizabeth University Hospital, NHS Greater Glasgow and Clyde Health Board, Glasgow, UKWest of Scotland Heart and Lung Centre, Golden Jubilee National Hospital, Glasgow, UK; Institute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, UKWest of Scotland Heart and Lung Centre, Golden Jubilee National Hospital, Glasgow, UK; Institute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, UK; Department of Cardiology, Queen Elizabeth University Hospital, NHS Greater Glasgow and Clyde Health Board, Glasgow, UKMI with non-obstructive coronary arteries (MINOCA) is caused by a heterogeneous group of vascular or myocardial disorders. MINOCA occurs in 5–15% of patients presenting with acute ST-segment elevation MI or non-ST segment elevation MI and prognosis is impaired. The diagnosis of MINOCA is made during coronary angiography following acute MI, where there is no stenosis ≥50% present in an infarct-related epicardial artery and no overt systemic aetiology for the presentation. Accurate diagnosis and subsequent management require the appropriate utilisation of intravascular imaging, coronary function testing and subsequent imaging to assess for myocardial disorders without coronary involvement. Although plaque-related MINOCA is currently managed with empirical secondary prevention strategies, there remains an unmet therapeutic need for targeted and evidence-based therapy for MINOCA patients and increased awareness of the recommended diagnostic pathway.https://icrjournal.com/articleindex/icr.2021.10 |
| spellingShingle | Robert Sykes Daniel Doherty Kenneth Mangion Andrew Morrow Colin Berry What an Interventionalist Needs to Know About MI with Non-obstructive Coronary Arteries Interventional Cardiology: Reviews, Research, Resources |
| title | What an Interventionalist Needs to Know About MI with Non-obstructive Coronary Arteries |
| title_full | What an Interventionalist Needs to Know About MI with Non-obstructive Coronary Arteries |
| title_fullStr | What an Interventionalist Needs to Know About MI with Non-obstructive Coronary Arteries |
| title_full_unstemmed | What an Interventionalist Needs to Know About MI with Non-obstructive Coronary Arteries |
| title_short | What an Interventionalist Needs to Know About MI with Non-obstructive Coronary Arteries |
| title_sort | what an interventionalist needs to know about mi with non obstructive coronary arteries |
| url | https://icrjournal.com/articleindex/icr.2021.10 |
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