Assessment of genetically modified maize MON 94804 (application GMFF‐2022‐10651)
Abstract Genetically modified (GM) maize MON 94804 was developed to achieve a reduction in plant height by introducing the GA20ox_SUP suppression cassette. The molecular characterisation and bioinformatic analyses do not identify issues requiring food/feed safety assessment. None of the agronomic/ph...
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2024-04-01
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| Online Access: | https://doi.org/10.2903/j.efsa.2024.8714 |
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| author | EFSA Panel on Genetically Modified Organisms (GMO) Ewen Mullins Jean‐Louis Bresson Tamas Dalmay Ian Crawford Dewhurst Michelle M. Epstein Leslie George Firbank Philippe Guerche Jan Hejatko Francisco Javier Moreno Hanspeter Naegeli Fabien Nogué Nils Rostoks Jose Juan Sánchez Serrano Giovanni Savoini Eve Veromann Fabio Veronesi Michele Ardizzone Giacomo De Sanctis Andrea Gennaro José Ángel Gómez Ruiz Paschalina Grammatikou Tilemachos Goumperis Sara Jacchia Paolo Lenzi Aleksandra Lewandowska Ana Martin Camargo Franco Maria Neri Pietro Piffanelli Tommaso Raffaello Kyriaki Xiftou |
| author_facet | EFSA Panel on Genetically Modified Organisms (GMO) Ewen Mullins Jean‐Louis Bresson Tamas Dalmay Ian Crawford Dewhurst Michelle M. Epstein Leslie George Firbank Philippe Guerche Jan Hejatko Francisco Javier Moreno Hanspeter Naegeli Fabien Nogué Nils Rostoks Jose Juan Sánchez Serrano Giovanni Savoini Eve Veromann Fabio Veronesi Michele Ardizzone Giacomo De Sanctis Andrea Gennaro José Ángel Gómez Ruiz Paschalina Grammatikou Tilemachos Goumperis Sara Jacchia Paolo Lenzi Aleksandra Lewandowska Ana Martin Camargo Franco Maria Neri Pietro Piffanelli Tommaso Raffaello Kyriaki Xiftou |
| author_sort | EFSA Panel on Genetically Modified Organisms (GMO) |
| collection | DOAJ |
| description | Abstract Genetically modified (GM) maize MON 94804 was developed to achieve a reduction in plant height by introducing the GA20ox_SUP suppression cassette. The molecular characterisation and bioinformatic analyses do not identify issues requiring food/feed safety assessment. None of the agronomic/phenotypic and compositional differences identified between maize MON 94804 and its conventional counterpart needs further assessment, except for ear height, plant height and levels of carbohydrates in forage, which do not raise safety or nutritional concerns. The Panel on Genetically Modified Organisms (GMO Panel) does not identify safety concerns regarding the toxicity and allergenicity of the GA20ox_SUP precursor‐miRNA and derived mature miRNA as expressed in maize MON 94804 and finds no evidence that the genetic modification would change the overall allergenicity of maize MON 94804. In the context of this application, the consumption of food and feed from maize MON 94804 does not represent a nutritional concern in humans and animals. The GMO Panel concludes that maize MON 94804 is as safe as the conventional counterpart and non‐GM maize varieties tested, and no post‐market monitoring of food/feed is considered necessary. In the case of accidental release of viable maize MON 94804 grains into the environment, this would not raise environmental safety concerns. The post‐market environmental monitoring plan and reporting intervals are in line with the intended uses of maize MON 94804. The GMO Panel concludes that maize MON 94804 is as safe as its conventional counterpart and the tested non‐GM maize varieties with respect to potential effects on human and animal health and the environment. |
| format | Article |
| id | doaj-art-d7ac961194df4ca1a2bcc14f5a887c02 |
| institution | Kabale University |
| issn | 1831-4732 |
| language | English |
| publishDate | 2024-04-01 |
| publisher | Wiley |
| record_format | Article |
| series | EFSA Journal |
| spelling | doaj-art-d7ac961194df4ca1a2bcc14f5a887c022025-08-20T03:30:44ZengWileyEFSA Journal1831-47322024-04-01224n/an/a10.2903/j.efsa.2024.8714Assessment of genetically modified maize MON 94804 (application GMFF‐2022‐10651)EFSA Panel on Genetically Modified Organisms (GMO)Ewen MullinsJean‐Louis BressonTamas DalmayIan Crawford DewhurstMichelle M. EpsteinLeslie George FirbankPhilippe GuercheJan HejatkoFrancisco Javier MorenoHanspeter NaegeliFabien NoguéNils RostoksJose Juan Sánchez SerranoGiovanni SavoiniEve VeromannFabio VeronesiMichele ArdizzoneGiacomo De SanctisAndrea GennaroJosé Ángel Gómez RuizPaschalina GrammatikouTilemachos GoumperisSara JacchiaPaolo LenziAleksandra LewandowskaAna Martin CamargoFranco Maria NeriPietro PiffanelliTommaso RaffaelloKyriaki XiftouAbstract Genetically modified (GM) maize MON 94804 was developed to achieve a reduction in plant height by introducing the GA20ox_SUP suppression cassette. The molecular characterisation and bioinformatic analyses do not identify issues requiring food/feed safety assessment. None of the agronomic/phenotypic and compositional differences identified between maize MON 94804 and its conventional counterpart needs further assessment, except for ear height, plant height and levels of carbohydrates in forage, which do not raise safety or nutritional concerns. The Panel on Genetically Modified Organisms (GMO Panel) does not identify safety concerns regarding the toxicity and allergenicity of the GA20ox_SUP precursor‐miRNA and derived mature miRNA as expressed in maize MON 94804 and finds no evidence that the genetic modification would change the overall allergenicity of maize MON 94804. In the context of this application, the consumption of food and feed from maize MON 94804 does not represent a nutritional concern in humans and animals. The GMO Panel concludes that maize MON 94804 is as safe as the conventional counterpart and non‐GM maize varieties tested, and no post‐market monitoring of food/feed is considered necessary. In the case of accidental release of viable maize MON 94804 grains into the environment, this would not raise environmental safety concerns. The post‐market environmental monitoring plan and reporting intervals are in line with the intended uses of maize MON 94804. The GMO Panel concludes that maize MON 94804 is as safe as its conventional counterpart and the tested non‐GM maize varieties with respect to potential effects on human and animal health and the environment.https://doi.org/10.2903/j.efsa.2024.8714GA20oxgenetic engineeringGMimport and processingmaize (Zea mays)MON 94804 |
| spellingShingle | EFSA Panel on Genetically Modified Organisms (GMO) Ewen Mullins Jean‐Louis Bresson Tamas Dalmay Ian Crawford Dewhurst Michelle M. Epstein Leslie George Firbank Philippe Guerche Jan Hejatko Francisco Javier Moreno Hanspeter Naegeli Fabien Nogué Nils Rostoks Jose Juan Sánchez Serrano Giovanni Savoini Eve Veromann Fabio Veronesi Michele Ardizzone Giacomo De Sanctis Andrea Gennaro José Ángel Gómez Ruiz Paschalina Grammatikou Tilemachos Goumperis Sara Jacchia Paolo Lenzi Aleksandra Lewandowska Ana Martin Camargo Franco Maria Neri Pietro Piffanelli Tommaso Raffaello Kyriaki Xiftou Assessment of genetically modified maize MON 94804 (application GMFF‐2022‐10651) EFSA Journal GA20ox genetic engineering GM import and processing maize (Zea mays) MON 94804 |
| title | Assessment of genetically modified maize MON 94804 (application GMFF‐2022‐10651) |
| title_full | Assessment of genetically modified maize MON 94804 (application GMFF‐2022‐10651) |
| title_fullStr | Assessment of genetically modified maize MON 94804 (application GMFF‐2022‐10651) |
| title_full_unstemmed | Assessment of genetically modified maize MON 94804 (application GMFF‐2022‐10651) |
| title_short | Assessment of genetically modified maize MON 94804 (application GMFF‐2022‐10651) |
| title_sort | assessment of genetically modified maize mon 94804 application gmff 2022 10651 |
| topic | GA20ox genetic engineering GM import and processing maize (Zea mays) MON 94804 |
| url | https://doi.org/10.2903/j.efsa.2024.8714 |
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