Voltage-gated ion channel dysfunction precedes cardiomyopathy development in the dystrophic heart.

Voltage-gated ion channel dysfunction precedes cardiomyopathy development in the dystrophic heart.

<h4>Background</h4>Duchenne muscular dystrophy (DMD), caused by mutations in the dystrophin gene, is associated with severe cardiac complications including cardiomyopathy and cardiac arrhythmias. Recent research suggests that impaired voltage-gated ion channels in dystrophic cardiomyocyt...

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Bibliographic Details
Main Authors: Xaver Koenig, Sandra Dysek, Stefanie Kimbacher, Agnes K Mike, Rene Cervenka, Peter Lukacs, Katrin Nagl, Xuan B Dang, Hannes Todt, Reginald E Bittner, Karlheinz Hilber
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0020300&type=printable
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