Congenital Heart Disease from Infancy to Adulthood: Pathology and Nosology
Congenital heart diseases (CHDs) are usually defined as structural anomalies of the heart and great arteries, present since birth, that are due to embryological maldevelopment, with overt or potential dysfunction. Nowadays, most of the patients with CHD in adulthood (age > 18 years) had been oper...
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MDPI AG
2025-04-01
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| Series: | Biomedicines |
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| Online Access: | https://www.mdpi.com/2227-9059/13/4/875 |
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| author | Gaetano Thiene Marny Fedrigo |
| author_facet | Gaetano Thiene Marny Fedrigo |
| author_sort | Gaetano Thiene |
| collection | DOAJ |
| description | Congenital heart diseases (CHDs) are usually defined as structural anomalies of the heart and great arteries, present since birth, that are due to embryological maldevelopment, with overt or potential dysfunction. Nowadays, most of the patients with CHD in adulthood (age > 18 years) had been operated on with success in infancy or childhood and undergo periodical screening. Pathology and nosology of CHDs are herein treated with special attention to adulthood according to the involved cardiac structures (aorta, valves, coronary arteries, myocardium, great arteries, conduction system). Moreover, the purpose is to postulate, in the era of molecular medicine, that genetically determined defects are also congenital cardiac disorders, with or without structural abnormality, and should be defined CHDs as well since their molecular background is material and present since conception. |
| format | Article |
| id | doaj-art-d7a75290dc6144d1ae5ed40504c2f83d |
| institution | DOAJ |
| issn | 2227-9059 |
| language | English |
| publishDate | 2025-04-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Biomedicines |
| spelling | doaj-art-d7a75290dc6144d1ae5ed40504c2f83d2025-08-20T03:14:27ZengMDPI AGBiomedicines2227-90592025-04-0113487510.3390/biomedicines13040875Congenital Heart Disease from Infancy to Adulthood: Pathology and NosologyGaetano Thiene0Marny Fedrigo1Cardiovascular Pathology, Department of Cardiac, Thoracic, Vascular Sciences and Public Health, Medical School, University of Padua, 35123 Padova, ItalyCardiovascular Pathology, Department of Cardiac, Thoracic, Vascular Sciences and Public Health, Medical School, University of Padua, 35123 Padova, ItalyCongenital heart diseases (CHDs) are usually defined as structural anomalies of the heart and great arteries, present since birth, that are due to embryological maldevelopment, with overt or potential dysfunction. Nowadays, most of the patients with CHD in adulthood (age > 18 years) had been operated on with success in infancy or childhood and undergo periodical screening. Pathology and nosology of CHDs are herein treated with special attention to adulthood according to the involved cardiac structures (aorta, valves, coronary arteries, myocardium, great arteries, conduction system). Moreover, the purpose is to postulate, in the era of molecular medicine, that genetically determined defects are also congenital cardiac disorders, with or without structural abnormality, and should be defined CHDs as well since their molecular background is material and present since conception.https://www.mdpi.com/2227-9059/13/4/875adulthoodbicuspid aortic valvecardiac surgerycongenital heart diseaseselderlymolecular pathology |
| spellingShingle | Gaetano Thiene Marny Fedrigo Congenital Heart Disease from Infancy to Adulthood: Pathology and Nosology Biomedicines adulthood bicuspid aortic valve cardiac surgery congenital heart diseases elderly molecular pathology |
| title | Congenital Heart Disease from Infancy to Adulthood: Pathology and Nosology |
| title_full | Congenital Heart Disease from Infancy to Adulthood: Pathology and Nosology |
| title_fullStr | Congenital Heart Disease from Infancy to Adulthood: Pathology and Nosology |
| title_full_unstemmed | Congenital Heart Disease from Infancy to Adulthood: Pathology and Nosology |
| title_short | Congenital Heart Disease from Infancy to Adulthood: Pathology and Nosology |
| title_sort | congenital heart disease from infancy to adulthood pathology and nosology |
| topic | adulthood bicuspid aortic valve cardiac surgery congenital heart diseases elderly molecular pathology |
| url | https://www.mdpi.com/2227-9059/13/4/875 |
| work_keys_str_mv | AT gaetanothiene congenitalheartdiseasefrominfancytoadulthoodpathologyandnosology AT marnyfedrigo congenitalheartdiseasefrominfancytoadulthoodpathologyandnosology |