Preventive aspirin use and its association with urinary incontinence in middle-aged and older adult males in the United States: a cross-sectional analysis of NHANES data

Background The association between preventive aspirin use and urinary incontinence (UI) among male adults remains poorly understand.Methods In this study, we analyzed data from the National Health and Nutrition Examination Survey (NHANES) collected in the 2011 ∼ 2018 cycle among US male adults, with...

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Main Authors: Bing-xin Lin, Rui-yao Zhao, Jian-wei Wu, Xiao-ling Chen, Wen-zhong Zheng
Format: Article
Language:English
Published: Taylor & Francis Group 2025-12-01
Series:The Aging Male
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Online Access:https://www.tandfonline.com/doi/10.1080/13685538.2025.2521815
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author Bing-xin Lin
Rui-yao Zhao
Jian-wei Wu
Xiao-ling Chen
Wen-zhong Zheng
author_facet Bing-xin Lin
Rui-yao Zhao
Jian-wei Wu
Xiao-ling Chen
Wen-zhong Zheng
author_sort Bing-xin Lin
collection DOAJ
description Background The association between preventive aspirin use and urinary incontinence (UI) among male adults remains poorly understand.Methods In this study, we analyzed data from the National Health and Nutrition Examination Survey (NHANES) collected in the 2011 ∼ 2018 cycle among US male adults, with aspirin use was defined as individuals self-reported use of aspirin. Multi-variable adjusted logistic regression models were used to analysis the association between aspirin use and UI.Results A total of 6844 male participants were evaluated in the study. Compared to participants without aspirin use, the individuals on aspirin with or without coronary heart disease (CVD), respectively, had higher incidences of urinary dysfunction including UI, urgent micturition, and nocturia. In addition, in multivariable logistic adjusted models, the risk of UI (OR = 2.44; 95%CI = 2.10–2.83; P-value = 0.0000) and urgent micturition (OR = 1.57; 95% CI = 1.35–1.83; P-value = 0.0000) in use participants was significantly greater versus the reference those who not taken aspirin.Conclusions The results of this study suggest that men who took aspirin were more likely to report symptoms of UI and urgent micturition. Therefore, reasonable use of aspirin may support the prevent and prevention of UI.
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publishDate 2025-12-01
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series The Aging Male
spelling doaj-art-d7a6848bf4f04629b047bc449220d32d2025-08-20T03:31:52ZengTaylor & Francis GroupThe Aging Male1368-55381473-07902025-12-0128110.1080/13685538.2025.2521815Preventive aspirin use and its association with urinary incontinence in middle-aged and older adult males in the United States: a cross-sectional analysis of NHANES dataBing-xin Lin0Rui-yao Zhao1Jian-wei Wu2Xiao-ling Chen3Wen-zhong Zheng4Department of Urology, Fujian Medical University Union Hospital, Fuzhou, ChinaDepartment of Urology, Fujian Medical University Union Hospital, Fuzhou, ChinaDepartment of Urology, Fujian Medical University Union Hospital, Fuzhou, ChinaDepartment of Intensive Care Unit, Fujian Medical University Union Hospital, Fuzhou, ChinaDepartment of Urology, Fujian Medical University Union Hospital, Fuzhou, ChinaBackground The association between preventive aspirin use and urinary incontinence (UI) among male adults remains poorly understand.Methods In this study, we analyzed data from the National Health and Nutrition Examination Survey (NHANES) collected in the 2011 ∼ 2018 cycle among US male adults, with aspirin use was defined as individuals self-reported use of aspirin. Multi-variable adjusted logistic regression models were used to analysis the association between aspirin use and UI.Results A total of 6844 male participants were evaluated in the study. Compared to participants without aspirin use, the individuals on aspirin with or without coronary heart disease (CVD), respectively, had higher incidences of urinary dysfunction including UI, urgent micturition, and nocturia. In addition, in multivariable logistic adjusted models, the risk of UI (OR = 2.44; 95%CI = 2.10–2.83; P-value = 0.0000) and urgent micturition (OR = 1.57; 95% CI = 1.35–1.83; P-value = 0.0000) in use participants was significantly greater versus the reference those who not taken aspirin.Conclusions The results of this study suggest that men who took aspirin were more likely to report symptoms of UI and urgent micturition. Therefore, reasonable use of aspirin may support the prevent and prevention of UI.https://www.tandfonline.com/doi/10.1080/13685538.2025.2521815Preventive aspirin usemale adultsurinary incontinencenational health and nutrition examination surveycoronary heart disease
spellingShingle Bing-xin Lin
Rui-yao Zhao
Jian-wei Wu
Xiao-ling Chen
Wen-zhong Zheng
Preventive aspirin use and its association with urinary incontinence in middle-aged and older adult males in the United States: a cross-sectional analysis of NHANES data
The Aging Male
Preventive aspirin use
male adults
urinary incontinence
national health and nutrition examination survey
coronary heart disease
title Preventive aspirin use and its association with urinary incontinence in middle-aged and older adult males in the United States: a cross-sectional analysis of NHANES data
title_full Preventive aspirin use and its association with urinary incontinence in middle-aged and older adult males in the United States: a cross-sectional analysis of NHANES data
title_fullStr Preventive aspirin use and its association with urinary incontinence in middle-aged and older adult males in the United States: a cross-sectional analysis of NHANES data
title_full_unstemmed Preventive aspirin use and its association with urinary incontinence in middle-aged and older adult males in the United States: a cross-sectional analysis of NHANES data
title_short Preventive aspirin use and its association with urinary incontinence in middle-aged and older adult males in the United States: a cross-sectional analysis of NHANES data
title_sort preventive aspirin use and its association with urinary incontinence in middle aged and older adult males in the united states a cross sectional analysis of nhanes data
topic Preventive aspirin use
male adults
urinary incontinence
national health and nutrition examination survey
coronary heart disease
url https://www.tandfonline.com/doi/10.1080/13685538.2025.2521815
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