Digital twins, synthetic patient data, and in-silico trials: can they empower paediatric clinical trials?
Summary: Randomised controlled trials are the gold standard to assess the effectiveness and safety of clinical interventions; however, many paediatric trials are discontinued early due to challenges in patient enrolment. Hence, most paediatric clinical trials suffer from lack of adequate power. Addi...
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| Main Authors: | ProfMD Mohan Pammi, Prakesh S Shah, MD, Liu K Yang, PhD, Joseph Hagan, ScD, Nima Aghaeepour, PhD, ProfMD Josef Neu, PhD |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2025-05-01
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| Series: | The Lancet: Digital Health |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S258975002500007X |
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