Synthesis and In Vitro Evaluation of a Scandium-44 Radiolabeled Nanobody as a PD-L1 PET Imaging Probe

Synthesis and In Vitro Evaluation of a Scandium-44 Radiolabeled Nanobody as a PD-L1 PET Imaging Probe

<b>Background/Objective</b>: Noninvasive PET imaging-based assessment of PD-L1 expression is of high clinical value for better patient selection and treatment response rates to PD-L1 immunotherapies. Due to their shorter biological half-life and faster clearance from the blood pool, radi...

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Bibliographic Details
Main Authors: Viktoria E. Krol, Aditya Bansal, Manasa Kethamreddy, Jason R. Ellinghuysen, Daniel J. Vail, Fabrice Lucien-Matteoni, Haidong Dong, Sean S. Park, Mukesh K. Pandey
Format: Article
Language:English
Published: MDPI AG 2025-06-01
Series:Pharmaceutics
Subjects:
Scandium-44
immunoPET
molecular imaging
PD-L1
breast cancer
Online Access:https://www.mdpi.com/1999-4923/17/6/796
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