The identification and validation of histone acetylation-related biomarkers in depression disorder based on bioinformatics and machine learning approaches

The identification and validation of histone acetylation-related biomarkers in depression disorder based on bioinformatics and machine learning approaches

BackgroundSome studies indicated that histone modification may be involved in depression disorder (DD). The maintenance of the histone acetylation state is the work of histone acetyltransferase (HAT) and histone deacetylase (HDAC), which is thought to be a potential diagnostic biomarker of depressio...

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Bibliographic Details
Main Authors: Lu Zhang, YuJing Lv, Mengqing Ma, Jile Lv, Jie Chen, Shang Lei, Yi Man, Guimei Xing, Yu Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-04-01
Series:Frontiers in Neuroscience
Subjects:
depression disorder
histone acetylation
hub genes
immune infiltration
bioinformatics
Online Access:https://www.frontiersin.org/articles/10.3389/fnins.2025.1479616/full
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https://www.frontiersin.org/articles/10.3389/fnins.2025.1479616/full

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