Rapid achievement of low disease activity during the use of a type I interferon inhibitor in a patient with torpid systemic lupus erythematosus (case report)

This article describes the experience of using the type I interferon inhibitor anifrolumab (AFM) in a patient with a torpid course of systemic lupus erythematosus. The reason for prescribing AFM was the need for a quick achievement of low disease activity due to a planned hip replacement. Dynamic ob...

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Main Authors: A. A. Baranov, E. A. Aseeva, S. K. Soloviev, N. Yu. Nikishina, E. A. Malygina, T. O. Abissova, Z. Yu. Pimenova, T. M. Reshetnyak, S. A. Makarov, N. A. Lapkina, A. M. Lila
Format: Article
Language:Russian
Published: IMA-PRESS LLC 2024-06-01
Series:Современная ревматология
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Online Access:https://mrj.ima-press.net/mrj/article/view/1591
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author A. A. Baranov
E. A. Aseeva
S. K. Soloviev
N. Yu. Nikishina
E. A. Malygina
T. O. Abissova
Z. Yu. Pimenova
T. M. Reshetnyak
S. A. Makarov
N. A. Lapkina
A. M. Lila
author_facet A. A. Baranov
E. A. Aseeva
S. K. Soloviev
N. Yu. Nikishina
E. A. Malygina
T. O. Abissova
Z. Yu. Pimenova
T. M. Reshetnyak
S. A. Makarov
N. A. Lapkina
A. M. Lila
author_sort A. A. Baranov
collection DOAJ
description This article describes the experience of using the type I interferon inhibitor anifrolumab (AFM) in a patient with a torpid course of systemic lupus erythematosus. The reason for prescribing AFM was the need for a quick achievement of low disease activity due to a planned hip replacement. Dynamic observational data over a six-month period confirmed that AFM enables a rapid achievement of low disease activity without increasing the dose of glucocorticoids, significantly improve the patient's quality of life and even prepare them for major surgery without exacerbating the underlying process.
format Article
id doaj-art-d7939f7d364b40d28150d2b59f8fe2fb
institution Kabale University
issn 1996-7012
2310-158X
language Russian
publishDate 2024-06-01
publisher IMA-PRESS LLC
record_format Article
series Современная ревматология
spelling doaj-art-d7939f7d364b40d28150d2b59f8fe2fb2025-08-20T03:59:56ZrusIMA-PRESS LLCСовременная ревматология1996-70122310-158X2024-06-01183717710.14412/1996-7012-2024-3-71-772687Rapid achievement of low disease activity during the use of a type I interferon inhibitor in a patient with torpid systemic lupus erythematosus (case report)A. A. Baranov0E. A. Aseeva1S. K. Soloviev2N. Yu. Nikishina3E. A. Malygina4T. O. Abissova5Z. Yu. Pimenova6T. M. Reshetnyak7S. A. Makarov8N. A. Lapkina9A. M. Lila10Yaroslavl State Medical University, Ministry of Health of RussiaV.A. Nasonova Research Institute of RheumatologyV.A. Nasonova Research Institute of RheumatologyV.A. Nasonova Research Institute of RheumatologyYaroslavl Regional Clinical HospitalYaroslavl Regional Clinical HospitalYaroslavl Regional Clinical HospitalV.A. Nasonova Research Institute of Rheumatology; Russian Medical Academy of Continuing Professional Education, Ministry of Health of RussiaV.A. Nasonova Research Institute of RheumatologyV.A. Nasonova Research Institute of RheumatologyV.A. Nasonova Research Institute of Rheumatology; Russian Medical Academy of Continuing Professional Education, Ministry of Health of RussiaThis article describes the experience of using the type I interferon inhibitor anifrolumab (AFM) in a patient with a torpid course of systemic lupus erythematosus. The reason for prescribing AFM was the need for a quick achievement of low disease activity due to a planned hip replacement. Dynamic observational data over a six-month period confirmed that AFM enables a rapid achievement of low disease activity without increasing the dose of glucocorticoids, significantly improve the patient's quality of life and even prepare them for major surgery without exacerbating the underlying process.https://mrj.ima-press.net/mrj/article/view/1591systemic lupus erythematosusinterferon receptorsinterferon αanifrolumab
spellingShingle A. A. Baranov
E. A. Aseeva
S. K. Soloviev
N. Yu. Nikishina
E. A. Malygina
T. O. Abissova
Z. Yu. Pimenova
T. M. Reshetnyak
S. A. Makarov
N. A. Lapkina
A. M. Lila
Rapid achievement of low disease activity during the use of a type I interferon inhibitor in a patient with torpid systemic lupus erythematosus (case report)
Современная ревматология
systemic lupus erythematosus
interferon receptors
interferon α
anifrolumab
title Rapid achievement of low disease activity during the use of a type I interferon inhibitor in a patient with torpid systemic lupus erythematosus (case report)
title_full Rapid achievement of low disease activity during the use of a type I interferon inhibitor in a patient with torpid systemic lupus erythematosus (case report)
title_fullStr Rapid achievement of low disease activity during the use of a type I interferon inhibitor in a patient with torpid systemic lupus erythematosus (case report)
title_full_unstemmed Rapid achievement of low disease activity during the use of a type I interferon inhibitor in a patient with torpid systemic lupus erythematosus (case report)
title_short Rapid achievement of low disease activity during the use of a type I interferon inhibitor in a patient with torpid systemic lupus erythematosus (case report)
title_sort rapid achievement of low disease activity during the use of a type i interferon inhibitor in a patient with torpid systemic lupus erythematosus case report
topic systemic lupus erythematosus
interferon receptors
interferon α
anifrolumab
url https://mrj.ima-press.net/mrj/article/view/1591
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