Detection of the novel IMP-38 among carbapenemase-producing Enterobacteriaceae in a university hospital, China
Introduction: This study set out to investigate the molecular epidemiology of carbapenemase-producing Enterobacteriaceae isolates collected from Xiang Ya Hospital, Hunan, China. Methodology: The carbapenemase genes from Enterobacteriaceae isolates were determined by PCR and sequencing. Relatedness...
Saved in:
| Main Authors: | , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
The Journal of Infection in Developing Countries
2014-08-01
|
| Series: | Journal of Infection in Developing Countries |
| Subjects: | |
| Online Access: | https://jidc.org/index.php/journal/article/view/4179 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1850036257218887680 |
|---|---|
| author | Zijuan Jian Yanming Li Wenen Liu Hongling Li Yunli Zhang Yanbing Li Xiumei Gu Wanchan Peng |
| author_facet | Zijuan Jian Yanming Li Wenen Liu Hongling Li Yunli Zhang Yanbing Li Xiumei Gu Wanchan Peng |
| author_sort | Zijuan Jian |
| collection | DOAJ |
| description | Introduction: This study set out to investigate the molecular epidemiology of carbapenemase-producing Enterobacteriaceae isolates collected from Xiang Ya Hospital, Hunan, China.
Methodology: The carbapenemase genes from Enterobacteriaceae isolates were determined by PCR and sequencing. Relatedness of Klebsiella pneumoniae isolates was evaluated by pulsed-field gel electrophoresis.
Results: Twenty-four out of 738 non-repetitive Enterobacteriaceae isolates harbored carbapenemase genes including IMP-38, a novel IMP-type metallo-enzyme. Nine IMP-38-producing isolates were shown to originate from the same clone and caused a small outbreak in the neonatal ward.
Conclusions: IMP-38, a novel IMP-type metallo-enzyme, was one of the predominant types of carbapenemase in the clinical carbapenem-resistant Enterobacteriaceae isolates in our hospital.
|
| format | Article |
| id | doaj-art-d792e95fe8a745acb5ded4d24ff1463a |
| institution | DOAJ |
| issn | 1972-2680 |
| language | English |
| publishDate | 2014-08-01 |
| publisher | The Journal of Infection in Developing Countries |
| record_format | Article |
| series | Journal of Infection in Developing Countries |
| spelling | doaj-art-d792e95fe8a745acb5ded4d24ff1463a2025-08-20T02:57:14ZengThe Journal of Infection in Developing CountriesJournal of Infection in Developing Countries1972-26802014-08-0180810.3855/jidc.4179Detection of the novel IMP-38 among carbapenemase-producing Enterobacteriaceae in a university hospital, ChinaZijuan Jian0Yanming Li1Wenen Liu2Hongling Li3Yunli Zhang4Yanbing Li5Xiumei Gu6Wanchan Peng7Xiangya Hospital, Central South University, 87 Xiangya Road, Changsha, Hunan, 410008, P. R. China.Xiangya Hospital, Central South University, 87 Xiangya Road, Changsha, Hunan, 410008, P. R. China.Xiangya Hospital, Central South University, 87 Xiangya Road, Changsha, Hunan 410008, P.R. ChinaXiangya Hospital, Central South University, 87 Xiangya Road, Changsha, Hunan, 410008, P. R. China.Xiangya Hospital, Central South University, 87 Xiangya Road, Changsha, Hunan, 410008, P. R. China.Xiangya Hospital, Central South University, 87 Xiangya Road, Changsha, Hunan, 410008, P. R. China.Xiangya Hospital, Central South University, 87 Xiangya Road, Changsha, Hunan, 410008, P. R. China.Xiangya Hospital, Central South University, 87 Xiangya Road, Changsha, Hunan, 410008, P. R. China.Introduction: This study set out to investigate the molecular epidemiology of carbapenemase-producing Enterobacteriaceae isolates collected from Xiang Ya Hospital, Hunan, China. Methodology: The carbapenemase genes from Enterobacteriaceae isolates were determined by PCR and sequencing. Relatedness of Klebsiella pneumoniae isolates was evaluated by pulsed-field gel electrophoresis. Results: Twenty-four out of 738 non-repetitive Enterobacteriaceae isolates harbored carbapenemase genes including IMP-38, a novel IMP-type metallo-enzyme. Nine IMP-38-producing isolates were shown to originate from the same clone and caused a small outbreak in the neonatal ward. Conclusions: IMP-38, a novel IMP-type metallo-enzyme, was one of the predominant types of carbapenemase in the clinical carbapenem-resistant Enterobacteriaceae isolates in our hospital. https://jidc.org/index.php/journal/article/view/4179carbapenemaseEnterobacteriaceaeIMPKPC |
| spellingShingle | Zijuan Jian Yanming Li Wenen Liu Hongling Li Yunli Zhang Yanbing Li Xiumei Gu Wanchan Peng Detection of the novel IMP-38 among carbapenemase-producing Enterobacteriaceae in a university hospital, China Journal of Infection in Developing Countries carbapenemase Enterobacteriaceae IMP KPC |
| title | Detection of the novel IMP-38 among carbapenemase-producing Enterobacteriaceae in a university hospital, China |
| title_full | Detection of the novel IMP-38 among carbapenemase-producing Enterobacteriaceae in a university hospital, China |
| title_fullStr | Detection of the novel IMP-38 among carbapenemase-producing Enterobacteriaceae in a university hospital, China |
| title_full_unstemmed | Detection of the novel IMP-38 among carbapenemase-producing Enterobacteriaceae in a university hospital, China |
| title_short | Detection of the novel IMP-38 among carbapenemase-producing Enterobacteriaceae in a university hospital, China |
| title_sort | detection of the novel imp 38 among carbapenemase producing enterobacteriaceae in a university hospital china |
| topic | carbapenemase Enterobacteriaceae IMP KPC |
| url | https://jidc.org/index.php/journal/article/view/4179 |
| work_keys_str_mv | AT zijuanjian detectionofthenovelimp38amongcarbapenemaseproducingenterobacteriaceaeinauniversityhospitalchina AT yanmingli detectionofthenovelimp38amongcarbapenemaseproducingenterobacteriaceaeinauniversityhospitalchina AT wenenliu detectionofthenovelimp38amongcarbapenemaseproducingenterobacteriaceaeinauniversityhospitalchina AT honglingli detectionofthenovelimp38amongcarbapenemaseproducingenterobacteriaceaeinauniversityhospitalchina AT yunlizhang detectionofthenovelimp38amongcarbapenemaseproducingenterobacteriaceaeinauniversityhospitalchina AT yanbingli detectionofthenovelimp38amongcarbapenemaseproducingenterobacteriaceaeinauniversityhospitalchina AT xiumeigu detectionofthenovelimp38amongcarbapenemaseproducingenterobacteriaceaeinauniversityhospitalchina AT wanchanpeng detectionofthenovelimp38amongcarbapenemaseproducingenterobacteriaceaeinauniversityhospitalchina |