LFA-1: A potential key player in microglia-mediated neuroprotection against oxygen-glucose deprivation in vitro.

LFA-1: A potential key player in microglia-mediated neuroprotection against oxygen-glucose deprivation in vitro.

For the last 38 years, all neuroprotective agents for patients with ischemic stroke have failed in clinical trials. The innate immune system, particularly microglia, is a much-discussed target for neuroprotective agents. Promising results for neuroprotection by inhibition of integrins with drugs suc...

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Main Authors: Robin Jansen, Marc Pawlitzki, Michael Gliem, Sven G Meuth, Stefanie Schreiber, Michael-W Görtler, Jens Neumann
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2025-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0314020
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